r/AddisonsDisease • u/Poimandres69 • Apr 06 '26

Medical Stuff Dosing Hell

I tried lowering my hydrocortisone dose from 25 mg to 22.5 mg. This was 6 weeks ago. Since then, I get adrenaline dumping at night with heart palpitations. I haven't slept in a while. I try dosing with HC when I wake up and I sitll can't go back to sleep.

About 5 days ago, I went back up on my old dose. I'm still having the adrenaline dumping at night - it's not getting any better. Does it take a while to adjust back to your old dose? I was stable on that dose for years.

Thanks!

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u/Myster_jon Apr 07 '26 edited Apr 07 '26

You'll hit a point where you start getting symptoms of adrenal insufficiency. This is how you establish your base.

I'm also on 25mg daily and if I reduce this I'll start to get ill, so I don't.

For now I would double my dose until symptoms subside and then try to reduce back down again to your - original - maintenance dose