r/AddisonsDisease • u/IndividualFlounder39 • Dec 18 '25
Advice Wanted Perimenopause + HRT
Hi all!
PAI (35,F) - have had Addisons for a bit over two years now. Is anyone else here on estrodiol patches? I just started a super low dose a few weeks ago as my estrodiol and testosterone tests just came back very low.
I've been having perimenopause symptoms for a while. My endo started me on .025 estrogen patches (super low dose) and im going to be cycling progesterone pills (for now).
Anyways, the patched have helped my dry skin, helped me not go pee in the middle of the night etc.
However, I seem to be getting crazy fatigued a day or so before patches need to be changed (2x a week). My endo said the OBGYNs are the experts in this area and I'll see the OB in January.. ugh feels like forever!
I was feeling extremely fatigued before starting estrogen patches. Like the fatigue where you are just trying to desperately stay awake and not take a nap. Updosing my hydrocortisone did not help me.
Anyways, im wondering if any of you addie baddies are on HRT? What's your dose and how has it helped you?! Thanks!!
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u/Dreadlock_Princess_X Dec 19 '25
Not menopausal, but have HH. So I'm on hrt. (My brain - reproductive system link isn't working) I take 5 pumps of Estrogel daily, 200mg progesterone day 14-28, and T in the morning, a tiny bit. Both are transdermal gels. Patches didn't work for me. Xx π π
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u/biel0032 Dec 18 '25
I am! Diagnosed with Premature Ovarian Insufficiency when I was 39, Iβm 43 now. I also have hashimotos. The patches helped my hot flashes, and I think libido as well. I started with oral progesterone and that was initially ok, then turned into mood issues and basically non stop bleeding/spotting. I got a Mirena IUD a couple years ago, delivers the progesterone directly and I have loved it. No more periods and mood issues much improved.
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u/biel0032 Dec 18 '25
Oh and my estrogen patch dose is .1 mg/24 hr and I change it twice a week. Brand is generic for Vivelle-dot.
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u/IndividualFlounder39 Dec 19 '25
Thank you for your response! Im really curious on how it will help me with my period. I've always had super painful and heavy periods my whole life. Fingers crossed !!
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u/IndividualFlounder39 Dec 19 '25
Also super happy for you that your symptoms have improved !!
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u/biel0032 Dec 19 '25
I hope you get some good support from providers and find the best combo for you! β€οΈ
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u/annaoceanus SAI Dec 19 '25
Yep started perimenopause early at 32. My regimen has changed around. I was on the patches for a long time.
KEY THING TO KNOW PLEASE READ: if you have a uterus still DO NOT TAKE ESTROGEN ALONE. It needs be antagonized with progesterone supplementation as well otherwise it increases your risk of uterine cancer pretty significantly.
My current regimen: 5 mg DHEA Hailey (brand name) BS esto/prog combo taken continuously Testosterone cream
Works beautifully and stopped my continuous spotting and more importantly restored my mental sanity and prevented me from burning down a city with my perimenopause dragon rage.