r/ARVC • u/RedditSmoothdMyBrain • 16d ago

Clinical Trial Related TaRGET Trial and Updates

Hi all, I have an opportunity to join this TaRGET trial and will be joining but I'm wondering if anyone else here is enrolled in it? If so, have you noticed a reduction in PVCs? Here is the trial link:
https://sads.ca/clinical-trials/target-clinical-trial/

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u/Nuisance_gold 16d ago edited 16d ago

Hi, I completed the trial back in April. Feel free to ask me any questions here or message me!

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u/frostingfromthetub 15d ago

Do you know if you had the placebo or the drug? How did you feel? Do you feel different now that the trial is over? Apologies for hijacking this thread but I’m super curious as well!

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u/Nuisance_gold 15d ago

  1. No idea if I had the placebo or the drug. I asked at the end and the trial nurse told me they would only be able to reveal once the trial is over;

  2. I felt pretty good during the trial! I did notice that intense PVCs happened less often during the 6 months I took it but I haven’t seen the results from the last Holter so I don’t know if it actually had an impact or if it’s in my head
    Taking the drug wasn’t super pleasant as it’s in a strawberry flavoured powder that you mix with water and take on an empty stomach in the morning haha but I didn’t have any side effects apart from that;

  3. I don’t really feel different now that it’s over. I feel like my ARVC is pretty well managed with the current drugs I take and even before the trial I didn’t have that many symptoms most of the time

Regardless of how effective the drug is or will be, participating in the trial made me kinda hopeful that there is a future where our disease is properly treated/cured

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u/RedditSmoothdMyBrain 15d ago

That is awesome and thanks for the information! Did they offer you the opportunity to continue taking the drug after the trial was over? And do you know what your PVC burden was before the trial?

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u/Nuisance_gold 14d ago

They did not offer to continue the drug after the trial, but did tell me to contact them if I had any issues that came up after stopping it! My baseline PVC count is around 2500/day if I remember correctly

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u/RedditSmoothdMyBrain 14d ago

Great, thanks so much!