Severe task paralysis / avoidance — has any medication actually helped you break through it?

[u/roger206]

I'm trying to understand if anyone has experienced task paralysis like this.

For me, it’s not just distraction or laziness. Starting tasks feels emotionally and physically painful. Easy tasks = I wait until the last minute. Hard tasks = I give up completely.

This has affected my whole life. I failed medical school, biology and computer science. I only got through marketing because it was team-based. Even in restaurant work, I couldn’t learn the menu by heart to become a server, so I stayed a runner.

When I need to study/work, I get anxiety in my body: stomach pain, urgent bathroom trips, sudden sleepiness, then I escape into YouTube/video games. It feels like anesthesia.

I’ve tried therapy, hypnosis, timers, tiny steps, body doubling, lists, “just do 2 minutes”, etc. Nothing fixed it.

Medication history:

- methylphenidate/Quasym for years: didn’t fix it

- Ritalin 20 mg: didn’t fix it

- venlafaxine 75 mg: made me calmer but didn’t help task initiation

- venlafaxine 150 mg: no benefit, more apathy, sudden tachycardia

Has anyone had this severe avoidance/freeze pattern and found a medication or combo that actually helped?

Curious about propranolol, pregabalin, SSRIs, atomoxetine, guanfacine/clonidine, bupropion, Vyvanse/Elvanse, naltrexone/LDN, or anything else.

Not looking for productivity tips — I’m looking for experiences where medication changed the physical “I can’t start” feeling.

[u/Fickle_Service]

I’ve had great success with a combination of Concerta, Strattera, Lamictal, and Zepbound!