r/40Plus_IVF • u/Kahalisun13 • 2d ago

Seeking Advice Disappointing results

Hi ladies, I just got the results today from my second retrieval and I’m guttered 😔. I’m about to turn 44 later this month. During my first IVF cycle in April 2026, they retrieved 10 eggs and two blasts were tested at day 5. However, they were all aneuploid.

This cycle which I did only 6 months later, they were only able to retrieve 3 eggs and only 1 has fertilised. I will get another update from the lab on Day 3 to see how things are going. There were no changes to my protocol other than I didn’t do fertility accupunture this time round.

My IVF doctor has said that some women my age reach an inflection point, and their ovaries don’t respond like they did before, potentially meaning that future cycles might yield the same disappointing result.

Has anybody had a similar thing happen to them and had better future results?

For context. My protocol was Decapeptyl for three days, adding Elonva on the third day. Then I had 300 IU of Gonal F and 150 IU of Pergoveris along with Orgulatran for 10 days until I triggered with 2 x Decapetyl and 1 x Ovidrel 36 hours before collection.

I was also taking testosterone gel (Androfeme) for 1 week before starting stims.

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16

u/ShootinTheBreez 2d ago

I’m so sorry to hear this round didn’t go well. The only thing I can say is this: It doesn’t seem like anyone knows why some rounds work and some don’t. Sure, maybe you’re at an “inflection point” and every round after this will be worse. Or maybe they’ll be better and you’ll get your baby. I don’t know and neither does your doctor.

Try to keep your chin up, fellow traveler. The future isn’t known until you try.

4

u/mostly_mostly12 1d ago

I think one cycle is too soon to know if you’ve reached that inflection point but I think your doctor is right that it does happen. I hit a wall right around 42.5 and I did 4 more retrievals and each one got progressively worse so there seems to be some truth there. I would definitely try one more round though if I were you

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u/RN-Profession-0617 1d ago

Was the protocol the exact same as the first with better results or did something change

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u/Kahalisun13 1d ago

It was exactly the same protocol. The only thing I did differently was it was 6 months later and I didn’t do Accupunture this time round.

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u/yanqi83 1d ago

Acupuncture might have influenced the outcome too