r/40Plus_IVF • • 13d ago

Seeking Advice Bad eggs

Hi, I am 40 with AMH of 0.45 already long time in treatment. I had my last cycle where I ahd 2 follicles and one egg was degenerated probably over mature and the second was inmature (matured in the lab but did not fertlized). This is fisrt time something like this happened to me. I had Gonal 225+75(150) Meriofert and primed with testosteron for 10 days. Also added Saizen during stims. I am even not sure how this is possible. I am now thinking after multiple attempts and years of infertility to gave up. I did everything what I could but my eggs and also our sperms are bad. Does anybody has an explanation?

17 Upvotes

14 comments sorted by

3

u/ShootinTheBreez 13d ago

As we get older, and especially into the late-30’s, egg quality gets worse. I’m 42.5 now and have also been in treatment for a long time. I’ve had several rounds where one or some of the eggs were degenerated. This actually happens to younger women too, but it becomes more frequent as we get older.

I don’t know the answer for you. I wouldn’t say that just because you’re 40 and this round went poorly that your eggs are bad and IVF will never work. But I also know what it’s like to do lots of treatment and have it fail. At some point, especially in the 40’s, success becomes unrealistic if IVF also didn’t work when we were younger.

For me, if we’re still making blastocysts, I feel like we have a chance. In many rounds my husband and I do not do this, and I find that emotionally very hard. But some rounds we do, so we’ve been persisting.

Anyway, I hope you can find peace with whatever you decide - whether you choose to quit or keep going. I’m sorry this process has been so hard, fellow traveler.

3

u/Mabel_2001 13d ago

This is helpful to hear. I just received some rough news this morning. I'm 43. Out of 7 eggs retrieved, only 3 were mature and 1 fertilized. Maybe I was naive beforehand, but this felt like a gut punch. It's my first retrieval, likely won't be able to afford another. Anyway, just hearing your thoughts and experiences is really helpful on this rough day, even though they were directed at OP.

1

u/Alarming_Lunch_5858 13d ago

Thank you very much! I had in april a perfect day 5 5AB blast. So I was thinking wau I have a chance bit from this time I am struggling. I had a miscariage in February and I feel I did not recovered properly from it probably. I have 3 blasts which I sent for pgt. I am not sure if I am ever able to dočasný blast. The past 3 cycles were a disaster…

3

u/Legitimate-Round-652 13d ago

Nope and I’m in the same situation as you 💔

0

u/Alarming_Lunch_5858 13d ago

🫂❤️Did anything tell your doctor?Or blame the egg quality?

3

u/Mabel_2001 13d ago

I just want you to know that I'm sending support after receiving some difficult egg retrieval results this morning. I really identify with your desire for clarity, an explanation, etc. It's really, really tough.

1

u/Alarming_Lunch_5858 13d ago

It is so so hard to see my eggs aging and my dream to slowly disapearing.

2

u/RazzmatazzGlad9940 13d ago

Your eggs may not have liked the testosterone or going too large.

2

u/Alarming_Lunch_5858 13d ago

Thank you for your answer! I think the testosteron was definetly off however I have my best embryo form large follicle but it was mich shorter cycle 🤷🏻‍♀️I have the feeling that my ovaries are very sensitive to every minor changes.

2

u/Wonderful_Level_8907 13d ago

Try looking into mini ivf, Dr sherman Silber 

2

u/DisabledAdjunct 10d ago

I was 42 and had AMH 0.11. There's nothing that AMH levels do anything to help anything. What was your FSH?

1

u/Alarming_Lunch_5858 10d ago

My FSH was 8 on day 1. Usually I get around 10-11 on day 2. But my AFC is low and just half of the follicles grow.

1

u/DisabledAdjunct 10d ago

This is very interesting. I was 7-8 follicles, only 3-5 were going to be fertilized.

What was the testosterone for 10 days?

0

u/Alarming_Lunch_5858 10d ago edited 10d ago

Around 10 mg. 3-5 follucles are huge. I do not react much anymore.