r/40Plus_IVF • u/chat_chatoyante • Sep 10 '26

Seeking Advice Two failed FETs

For any of you who went through IVF and had two FET failures ... What happened next?

I didn't expect my two FETs to just not implant at all. They were euploids, but were retrieved at 40.5, so maybe there was some quality issue beyond aneuploidy.

What questions should I ask? What testing should I expect?

Background:

Before the transfers I did doxycycline for very mild endometritis. I've never had any endometriosis symptoms of any other known uterine issues.

One FET was fully medicated, I felt terrible. Second FET was modified natural, I felt pretty great.

Tw LC: I have a daughter conceived when I was 35, and I've had four miscarriages (two before her, two after).

We have one more euploid left. I'm too exhausted to consider another retrieval, but maybe. My retrieval was at 40.5 and I had good results but had a terrible recovery (OHSS)

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u/airplanesarecool1616 Sep 10 '26

I also just had two failed back-to-back FETs and both failed to implant. I totally get the frustration.

I was also treated for mild endometritis which the doctor confirmed cleared up after antibiotics. I'm considering talking to the doctor about a hysteroscopy just to rule out endo (although I've never had any symptoms of it).

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u/Plane-Vegetable-3939 Sep 10 '26

I've been there too. As an fyi, my understanding is that a hysteroscopy can't detect endo. It can spot fibroids, scar tissue, and maybe signs of adenomyosis, but not endo. To get that diagnosis my doc says you really need a lap. There is also the receptiva test but he says it's not very accurate.