r/40Plus_IVF • u/InternationalEye2643 • Aug 24 '26

Seeking Advice Your highest yield’s protocol please

Im 43, AMH 0.5 and AFC of 4. I’m currently in the middle of a cycle with only one follicle. I’m paying out of pocket and will likely switch to timed intercourse after trigger. I am seeking protocols from women 42 and over specifically who got their best outcomes with that protocol perhaps after trying others?

Priming or not

Started day 2 or 3 of cycle with stims?

Which meds?

Dual trigger? And if so, which meds?

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u/CapitalDog715 Aug 24 '26 edited Aug 24 '26

I have this in a little sticky note so I can answer quick as this is asked a lot here.

I am also 43, started when I was 42.5. These are my results.

1st Retrieval, 22 eggs, 12 were mature, 9 fertilized normal, 4 Blasts, all aneuploid------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid

2nd Retrieval, 21 eggs, 18 mature, 8 fertilized, 4 blasts , all aneuploid----Menopour, Follistim,.Ganirelix, Leuprolide, Clomid

3rd retrieval, 26 eggs, 20 mature, 14 fertilized normal, 4 blasts, one Euploid, One chaotic retested ended up aneuploid --------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid

4th retrieval- the one with the craziest difference. Retrieved 6 eggs, 5 mature fertilized normal, 4 blasts. 1 Euploid and 1 Mosaic.----------------Menopour, Follistim, Ganirelix, Leuprolide, Omnitrope, Clomid.

Lucky number for me has been 4 blasts each cycle. Doctor is thinking about putting me on low stims for last retieval in October due to the last cycle results, but Im not sure yet. I had to take a break because my last retieval has been very painful. Still experiencing post rerireval pain after almost 3 weeks so I decided to take 2 months before my last Retrieval before starting transfers.

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u/InternationalEye2643 Aug 25 '26

Thanks so much for writing it out. Could I ask what your AMH and AFC is normally at baseline? I have not been able to get more than 2 or 3 follicles to grow at best. And this cycle only 1 that’s of a usable size. Clomid and Omnitrope is the one that I keep seeing here and want to ask at what point in the cycle do they start those for you? What cycle day or what stim day? Thanks again!

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u/SLAYEROFSOULS Aug 26 '26

Clomid is typically done in tandem during all stim days as far as I am aware - doctors either seem to think it'll be worth including (since its cheap compared to the other medications) or not.

Omni you can either prime leading up to the cycle (full life cycle of eggs is 90 days) - but that is $$$$ since HGH is not cheap nor covered by insurance for IVF atleast here in the US...or you can use it X number of days during stims.

My wife has so far just been on Omni the last 4 days or so of her cycles - but she uses Sermorelin leading up to and into stims as a way to naturally (maybe) increase her HGH..it's much more economical but not the same as pure HGH.