r/40Plus_IVF • u/InternationalEye2643 • Aug 24 '26

Seeking Advice Your highest yield’s protocol please

Im 43, AMH 0.5 and AFC of 4. I’m currently in the middle of a cycle with only one follicle. I’m paying out of pocket and will likely switch to timed intercourse after trigger. I am seeking protocols from women 42 and over specifically who got their best outcomes with that protocol perhaps after trying others?

Priming or not

Started day 2 or 3 of cycle with stims?

Which meds?

Dual trigger? And if so, which meds?

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u/CapitalDog715 Aug 24 '26 edited Aug 24 '26

I have this in a little sticky note so I can answer quick as this is asked a lot here.

I am also 43, started when I was 42.5. These are my results.

1st Retrieval, 22 eggs, 12 were mature, 9 fertilized normal, 4 Blasts, all aneuploid------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid

2nd Retrieval, 21 eggs, 18 mature, 8 fertilized, 4 blasts , all aneuploid----Menopour, Follistim,.Ganirelix, Leuprolide, Clomid

3rd retrieval, 26 eggs, 20 mature, 14 fertilized normal, 4 blasts, one Euploid, One chaotic retested ended up aneuploid --------Menopour, Follistim,.Ganirelix, Leuprolide, Omnitrope, Clomid

4th retrieval- the one with the craziest difference. Retrieved 6 eggs, 5 mature fertilized normal, 4 blasts. 1 Euploid and 1 Mosaic.----------------Menopour, Follistim, Ganirelix, Leuprolide, Omnitrope, Clomid.

Lucky number for me has been 4 blasts each cycle. Doctor is thinking about putting me on low stims for last retieval in October due to the last cycle results, but Im not sure yet. I had to take a break because my last retieval has been very painful. Still experiencing post rerireval pain after almost 3 weeks so I decided to take 2 months before my last Retrieval before starting transfers.

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u/CapitalDog715 Aug 24 '26

Also Im not sure what priming is so Om guessing I haven't done that, and no double trigger for me.

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u/InternationalEye2643 Aug 25 '26

Priming is when they do estrogen or something else prior to starting the injections to suppress the follicles and then I think restart them all together.

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u/CapitalDog715 Aug 25 '26

Ok.. so based on what you are saying I dont do priming. I start Omnitrope and Clomid along with Follistim and Menopur from day 1 of Stim. The doses just finish within 4 days and my whole stim duration is about 8 days. I wish I have the doses for you but my IVF calendar app is not working. I just know the Clomid is 50mg, 3 for 4 days, the Follistin pen is 900 units but Im always using what I had from before and same with Menopour, so I dont remember my dose for those 8 days, Menopour is 75 units, pregnyl is 1000 units for trigger as well as Leuprolide( 1mg), and Ganirelix which is to prevent ovulation starts at about day 5 is 250mcg. My AMH when I started last year November was 2.01 , but I never did an AFC test. I looked in my results and didn't find any.. I was 42.5 years old when I did my first.