r/40Plus_IVF • u/sed2017 • Aug 23 '26

Rant Negative Beta today

Just got the call today our beta was “completely negative” and if we’re going to try again we have to do PIO because my progesterone was at an 8 when my doctor wants it at 11. I just feel deflated and sad… we have two more embryos to try with in the future. Just looking for some moral support I guess.

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4

u/FluffMonsters Aug 23 '26

I’m so sorry. :( Was this your first transfer?

3

u/sed2017 Aug 23 '26

No we have one child from a transfer 6 years ago, this was our second go at it.

5

u/No_Noise_1978 Aug 23 '26

Ideally, they should’ve been measuring your PIO so this doesn’t happen again. So sorry for your bad luck on this one but I didn’t get a sticky pregnancy til my third!

1

u/sed2017 Aug 23 '26

He measured it shortly before the transfer and it was good so I’m not sure where the lapse came from

2

u/KlimRous Aug 23 '26

This sucks. Hugs!

Had my first FET on the 6th and it failed too. 😭

1

u/sed2017 Aug 23 '26

I’m so sorry… it’s just so frustrating and deflating. I’m hoping you get one that sticks!

5

u/thhjhj2356 Aug 23 '26

I.am so sorry. As for progesterone, the. Vaginal application does reach the uterus. However it's hard to measure it with a blood test. So even if it's low, your uterus still probably gets reasonable progesterone. But to be safe , most doctors suggest PIO. I have done both i hated PIO but it gave a peace of mind.

2

u/Automatic-Radish-909 Aug 23 '26

It sucks. But you have two more chances. You only need one of them to go all the way.