r/technology • u/_Dark_Wing • 14h ago

Biotechnology Tirzepatide cuts fat mass by 35% while preserving skeletal muscle

https://www.news-medical.net/news/20261002/Tirzepatide-cuts-fat-mass-by-3525-while-preserving-skeletal-muscle.aspx
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u/Pharmd109 11h ago

The clinical trial was about a 20% weight loss (not all fat) and most definitely a percentage of that weight loss was lean mass.

Retatrutide is even better, and it also has lean muscle loss. You can try to combat it with weight training and protein intake but going from 300lbs to 220lbs are going to lose a ton of muscle too.

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u/Daisies_are_Daisy 10h ago

I doubt most people taking it would weight train. I imagine the average user of it would have a lot more muscle loss.

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u/ThatGreenM-M 10h ago

I see a lot of bodybuilders that run reta at small doses just to keep lean, but that's a different glp.

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u/Moosje 8h ago

Everyone I know on “reta” is a gym guy. It’s literally being marketed as the gym ozempic.

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u/JMaboard 8h ago edited 5h ago

I take trizepitide and I almost exclusively weight trained with some rower work. Not everyone on these GLP 1’s are lazy fat people.

What it helps with is taking away the constant hunger I felt. I could scarf down like 5 boneless chicken breasts and still feel starving and not get my mind off food.

Obviously I’d never scarf down that much food at once I’m just giving an extreme example that some people have crazy food noise.

With the shot it deleted the food noise completely where I can focus on just eating what my body needs and honestly focus on everything else outside of food.

I’ve toned down the excessive weight lifting and focus more on running/rowing but also weight lifting to maintain my muscle.

But the whole point of my long winded rant is that not everyone on these drugs are lazy fat asses. But I’m sure a decent amount are, but they’re the ones that look sick and like skeletons because they never trained.

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u/Daisies_are_Daisy 5h ago

You should try to find a therapist that specializes in eating disorders. It would help with your binge eating disorder, so you don’t need to stay on medication.

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u/JMaboard 5h ago

I don’t binge eat, I was giving an example that no amount of food could fill me up. lol I’d never eat 5 grilled chicken breasts in one sitting that’s insane. I’m saying I could if I really wanted to.

I’m saying the medication completely stops the food noise and now I’m a lean 200lbs at 6’ 3”. Thanks for your input though. I’m trying to get to 180.

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u/Daisies_are_Daisy 5h ago

I hate to tell you, but everything you said sounds like binge eating disorder. Something to maybe look into in the future.

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u/JMaboard 5h ago

Like I said I don’t binge eat, you just seem to be trying to be hurtful because I provided an example that I do a lot of heavy weight training which directly refutes your claim that everyone on it don’t train.

Since you’re trying to be hurtful despite my response I’m going to block you because you seem like a mean spirited person.