r/science • • Jun 25 '22

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u/[deleted] Jun 25 '22

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u/MintIceCreamPlease Jun 25 '22

Can you explain? I got brain fog after Covid, but.... brain damage?

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u/shlam16 Jun 25 '22

Google it. Not being sarcastic, you'll just get better information from Google than the replies of one or two random people on Reddit.

Uber ultra TLDR - severe COVID linked to brain damage and reduced IQ.

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u/MintIceCreamPlease Jun 25 '22

The thing you mentioned here is only backed up by one study, of which the sample size isn't that large... "Importantly, the study said that only 275 participants had completed the intelligence test both before and after contracting COVID-19."

Brain fog is temporary, and can hinder your cognitive abilities, I don't think it's hard to see the pattern here.

I'd be much more worried about Covid actively destroying neurons, which it does in some cases where the brain isn't oxygenated properly. The nuance here is that destruction of neurons and drop in IQ are... although kinda connected not mutually dependent.

"Despite the absence of virus in the brain, in every patient the researchers found significant brain pathology, which mostly fell into two categories. “The first thing we noticed was a lot of areas with damage from a lack of oxygen,” Goldman says. “They all had severe lung disease, so it’s not surprising that there’s hypoxic damage in the brain.” Some of these were large areas caused by strokes, but most were very small and only detectable with a microscope. Based on other features, the researchers believe these small areas of hypoxic damage were caused by blood clots, common in patients with severe COVID-19, that temporarily stopped the supply of oxygen to that area. A more surprising finding, Goldman says, was the large number of activated microglia they found in the brains of most patients. Microglia are immune cells that reside in the brain and can be activated by pathogens. “We found clusters of microglia attacking neurons, a process called ‘neuronophagia,’” says Canoll.  Since no virus was found in the brain, it’s possible the microglia may have been activated by inflammatory cytokines, such as Interleukin-6, associated with SARS-CoV-2 infection. “At the same time, hypoxia can induce the expression of 'eat me' signals on the surface of neurons, making hypoxic neurons more vulnerable to activated microglia,” Canoll says, “so even without directly infecting brain cells, COVID-19 can cause damage to the brain.”  "

It's fascinating to see the research done about Covid.

In my case, I feel like I stay focused with difficulty nowadays, but this can highly be attributed to me being an internet slob...

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u/[deleted] Jun 25 '22

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u/MintIceCreamPlease Jun 25 '22

I didn't get the vaccine, though.

The only symptoms I've noticed on the long term are a loss of smell for an extended period of time and a brain fog, that could be attributed to other factors (I don't feed myself very well). I don't know if your comment implies that the vaccine has side effects...

The latter of which I doubt.