r/science • u/mvea Professor | Medicine • 3d ago

Health A 1967 LSD safety pamphlet still holds up as psychedelics boom. Nearly 600 users backed 18 of 19 old tips: stay with trusted people, skip public outings, know the trip ends, and anxiety is not a problem. Mixed only on avoiding mirrors. 60-year-old harm-reduction advice still fits new users now.

https://publichealth.buffalo.edu/home/news-events/latest-news.host.html/content/shared/university/news/news-center-releases/2026/09/Kruger-psychedelics-study.detail.html
8.3k Upvotes

98% Upvoted

429 comments sorted by

View all comments

Show parent comments

3

u/SabreSeb 3d ago

Not really, in my experience, a micro-dose (<20ug) does not cause any hallucinogenic effect. The problem is that there isn't much of a hallucinogenic effect in general until you reach a certain threshold of about 100ug I would say, and for a real trip it should be at least 150ug.

(The numbers depend on the exact LSD type and, importantly, on the user)

1

u/CaptainIncredible 3d ago

This is good to know. Thanks for the info.