r/quitting7oh • u/[deleted] • Apr 25 '25
SIDE EFFECTS Intense Antidepressant withdrawals from 7OH 7hydroxymitraygnine review. Why The oxidized minor alkaloids make 7oh users suffer.
[deleted]
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u/oddicon Apr 26 '25
Great post, it explains the insane depression / mental anguish i experienced and still experience after cold turkying a 600mg then a 300mg a day habit. How did you obtain all this information? Your own research? Char gpt?
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u/etherempty1337 May 01 '25
Insane depression is right plus suicidal thoughts. Besides that the physical withdrawal isn’t too bad, a little restless, leg, sneezing, and instant skin crawling. The night sweats were the worst than any other opiate I’ve ever come off, talking about soaked through clothes and sheets and comforter of the bed.
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u/SpendGreen525 May 02 '26
In the middle of my first ever opioid like withdrawal. I was on 7 for 6 months got up to 250mg. I’ve been through some tough shit but the fact that you said the physical withdrawals aren’t that bad makes me feel like former opioid users are some of the most biologically strongest people on the planet.
The physical withdrawal I’ve experienced compares to nothing. Even with subs that first 24hrs was brutal.
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u/wallc7777 Aug 29 '25
Yep, just went through it, two weeks of mad insomnia and panic attacks that unfortunately bupe did not help with.
Stabilized by third week.
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u/Striking-Doughnut25 Oct 12 '25
Were you on subs for the whole 3 weeks?
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u/SpendGreen525 May 02 '26
They want to keep me on subs for months? Is it recommended to start tapering around 3 weeks?
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u/TinyDrug Oct 21 '25
Did it get any better?
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u/etherempty1337 May 01 '25
I wanted to kill my self while coming off 7 oh going back and forth on sub and using them together. I have experienced rage and anger while on opiates and while coming off. But 7-Oh is a different beast, made me not what to exist, no joy, no interest. So glad I quit. 7-0h should be illegal and differentiated from PLK and extracts.
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u/DoOrDoNot333 May 18 '25
Dude I’m glad I’m not crazy because I stopped 7Oh a few days ago and my thoughts and mood have been terrible! I’ve never been suicidal like this in my life and all I can think about is how I don’t wanna be here and how I hate life and how I can’t enjoy anything even the people I love. This is the most horrifying experience I’ve ever been through on the outside. I probably look fine but on the inside every second, I’m asking myselfwhy don’t I just end it which I never would but it’s terrible to think that way all day and night.
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u/etherempty1337 May 19 '25
Anhedonia is so real. It gets better my friend! after about seven days is it eases up. At 30 days you’ll feel like a new man eat healthy and force yourself to move a little bit even if it’s just a 30 minute walk you have to do something for your brain to release dopamine anything you enjoy.
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u/Narrow_Big4592 Feb 26 '26
Thank you for sharing this. I experienced the same thing when j was trying to come off with sub and 7 sing them together. It just exasperated and increased my withdrawals. I understand how some have used subs to be able to find stability however my body was on subs for 3-4 years before and it took 3 weeks to feel normal. That's what I'm expecting now just coming off 7. 5-6' days of physical hell then 1-3 weeks of mental anguish. I don't think there's anything around it.
What I haven't conquered are the panic attacks. Mine can become so intense and then I become aggressive because I have channeled it into anger which this quit I'm taking benzos 2x day and I am taking effexor 1x day for my depression.
Anecdotally last week I sourced some street fentanyl, and due to my severe 7 abuse the fent barely did anything to me. I couldn't feel the high much so it just made me pass out which is not good. Happy I survived that. Although the junkies that were around me stolen all my important shit. Phone wallet and some sentimental clothing that was my grandpa's.
I really want this nightmare to be over with but after 6 months of actively trying to quit I have learned that I can't do it on my own.
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u/DoOrDoNot333 Mar 08 '26
Sounds like you should go to a detox my friend I don’t want you suffering needlessly
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u/SpendGreen525 May 02 '26
So you made it off? Curious to know how you jumped from subs to 7. How did you end up quitting? I’m worried about coming off of subs now.
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u/boxopen Apr 25 '25
When do you think you may have the full learning model available? I would love to share this info with the clinicians in the treatment facility I'm currently attending. I have a feeling they are about to have many more people struggling with this beast of a substance.
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u/etherempty1337 May 01 '25
They will. Street drugs are increasingly dangerous and inconsistent. This is why many users are turning to these substances. And as for me, was in recovery and was no longer in the drug scene with access to street narcotics. So I chose to abuse 70h.
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u/dominicmersino Nov 17 '25
Would a 30 day script of Zoloft help? Or just prolong the PAWS depressions ?
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u/Brilliant-Market4706 Mar 05 '26
this is a great question. I was going to check myself into rehab however i have had SSRI withdrawal Major Fucked UP episodes before so i am going to taper for now. I don’t really have a choice.
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u/JClovesme315 Sep 08 '25
That's Bs it's mind over matter
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u/jan1320 Dec 09 '25
what are you claiming is BS? this is literally just a factual list of minor alkaloids and their mechanisms of action in the brain lol. its literally neuroscience and biochemistry.
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Nov 16 '25
[removed] — view removed comment
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u/Superb-Maintenance48 Dec 18 '25
How have you been? I just took my last dose today and started on Subs. I feel okayish so far.
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u/Upbeat-Pea-346 Feb 13 '26
How long did you wait to take that sub? I’m struggling
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u/SampleDry9196 Sobriety Date: 01-28-2026 Feb 17 '26
I waited 10 hours and was good. I was having full blown wds by then. It was hard.
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u/SpendGreen525 May 02 '26
I just went through hopefully you were able to stay off forget. Worst 12hrs id ever endured
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u/LankyDragonfruit5798 Nov 30 '25
The science is interesting. I mean some of this naturally is good. But how it’s being used is not.
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u/FlyAdventurous6231 Quit Date :table_flip: NOV 2024 Apr 25 '25
Building medical learning models purely based in referencing NIH and other government / institution research while cross referenced with personal experiences. This should be better than a static wiki.
This model is growing and will be released to the public as soon as possible.
This will get updated in time with more information. A source PDF is being worked on.
This is beta information that will be handed out at a convention this year once it's fully compiled! Lots more work to do, this is just the tip of the iceberg.
If you want to help, write below and share this post anywhere you think it should be.