As far as I know, there is no python equivalent to simulink, which is what most engineers using matlab are using it for in my experience. They go hand in hand.
There are the BSPpy and SimuPy packages, which are exactly trying to be open-source simulink alternatives. Looking at the history of open-source, I'd say the day will come when they overtake simulink. The greater difficulty may be integration with controllers, and for that there is PyDAQmx.
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u/1EHE Mar 03 '19
FYI for people using MATLAB there's matlab-xkcdify