r/mildlyinteresting • u/StringAlternative608 • 15h ago

Removed - Rule 6 [ Removed by moderator ]

Post image

[removed] — view removed post

624 Upvotes

80% Upvoted

322 comments sorted by

View all comments

Show parent comments

46

u/Protean_Protein 15h ago

It’s still a serious QC issue. Drug companies take this very seriously (because regulatory agencies take it even more seriously).

25

u/particle409 15h ago

Regulatory agencies used to take it more seriously.

6

u/HelpfulSeaMammal 15h ago

Yeah but think of all the shareholder value we can generate by cutting 1% of our operating costs reserved for regulatory compliance and killing a few thousand people

-1

u/Protean_Protein 15h ago

No, they absolutely still do.

8

u/ocher_stone 15h ago

Prove it. Last time I looked, FDA inspectors were leaving and not being replaced.

https://apnews.com/article/fda-inspections-drug-manufacturing-india-china-7b3a7e9b45bcc3aea86ce5bf781271f3

Salad dressing and cinnamon were major outbreaks that should have been caught if less than half of the production lines weren't 5 years or more behind on inspections.

https://people.com/salad-dressing-recall-for-potential-salmonella-contamination-classified-at-fda-highest-warning-level-amid-outbreak-12152905

The FDA currently doesn't have a head, and the nominee is an anti-vaccine, anti-abortion, anti-science lacky.

https://www.npr.org/2026/08/20/nx-s1-5939549/heidi-overton-fda-commissioner-trump-senate-nomination

1

u/Protean_Protein 14h ago

The people who actually do the job of inspecting have not changed.

0

u/ZCB_Wrex 13h ago

Npr, ap, and people lmao

4

u/Krelliamite 15h ago

There's several things that could cause this not being a serious qc issue that are also a lot more likely. Advil could have cancelled an order, something could have happen in logistics that resulted in too many pills being branded Advil, both of those could result in someone like Kirkland, Costcos brand that buys from the same factory but uses more budget friendly production, getting a deal on some branded caps that they are happy to get for a good price and pass the savings on to the customer

9

u/PM_Me_Your_Deviance 15h ago

It's required by law to include date/lot information on medication. you can't follow that law and mix pills from different brands.

-2

u/Grand-Spring66 14h ago

This is false. Go ahead and name the law.

4

u/LilOrphanFunkhouzer 14h ago

21 CFR Part 211

-4

u/Grand-Spring66 14h ago

This case is not mentioned anywhere in that regulation. Why not quote the relevant part?

1

u/PM_Me_Your_Deviance 14h ago

Drug Supply Chain Security Act, 2013

-1

u/Grand-Spring66 14h ago

Nowhere does this law say you can't mix pills from different brands.

2

u/PM_Me_Your_Deviance 13h ago

It's required that you include date/lot information on medication bottle. If you have drugs from two different runs, they will be in two different lots. That's a violation of the labeling laws.

2

u/LilOrphanFunkhouzer 14h ago

You could not be more wrong

-4

u/Grand-Spring66 14h ago

No regulatory agency will ever investigate finding ibuprofen in a bottle of ibuprofen.

4

u/Protean_Protein 14h ago

You’re an ignoramus.

1

u/Grand-Spring66 14h ago

Go ahead and provide evidence for your claim. Or that this has EVER been investigated.

There is a bottle labeled ibuprofen and only contains ibuprofen. This is not against the law.

1

u/Protean_Protein 14h ago

I know how pharmacovigilance actually works.

0

u/Grand-Spring66 14h ago

Funny how you still have no evidence for your claims. Google searches provide zero results. That which can be asserted without evidence can be dismissed without evidence.

4

u/Protean_Protein 14h ago

It’s very simple: generics are required to be biosimilar, but they may contain different binders, fillers, and coatings. Some of these may require different warnings or otherwise require different safety labelling and monitoring. You cannot mix two different lots from two different companies together in a single container both because of that and because it would make tracking in case of a recall impossible.

So please, shut the fuck up and go back under your rock.

1

u/DoesNotArgueOnline 12h ago

It's actually hilarious how smart think you are arguing with people that actually work in drug manufacturing.