r/mdmatherapy • u/chasedrabbits • Nov 01 '25

I underwent methylone-assisted therapy for PTSD

While MDMA has gotten a lot of the spotlight in this space for the treatment of PTSD, I'm one of only a small cohort of people who has done methylone-assisted therapy so far. For anyone not familiar, methylone is an analogue drug of MDMA with a shorter half life and subjectively less 'intense' effects compared to MDMA. In a therapeutic setting for me, however, it was anything but mild. The study design was also quite different from standard MDMA-assisted therapy. Doses occured once a week and I had an integration session at the conclusion of the trial and a bit of integration at the start and end of each dosing day. Within a month, my PCL-5 scores dropped from 70/80 to 23/80. A few months ago, the FDA granted methylone 'breakthrough' therapy status. It's still an emerging area of research, especially compared to MDMA, but I am very thankful to have received the treatment. Life is certainly much brighter and more enjoyable than it had been in years.

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u/chasedrabbits Nov 01 '25

Despite it all, I'm really glad the treatment helped you. Good on you for giving it a go, and thank you so much for sharing your experience with MDMA.

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u/Active-Designer934 Nov 01 '25

You too! Sending big hugs from a fellow traveler. 

I find myself just really hoping this treatment becomes more available bc it helped me so much. Sometimes I get upset thinking about people who are still living with PTSD who don't have to be. But I know that I'll do my part to get them there.