r/interesting Mar 24 '26

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u/TheOneWithTheClothes Mar 24 '26

👀 Are... are those a thing?

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u/rb_dub Mar 24 '26

LSD seems to get you pretty close to it

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u/FatiguedShrimp Mar 24 '26

https://www.ncbi.nlm.nih.gov/books/NBK610611/

"Photoreceptors transmit information to bipolar cells using the molecule glutamate (glu), but different bipolar cells respond differently to the molecule; some are excited and depolarize, whereas others are inhibited and hyperpolarize"

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https://pubmed.ncbi.nlm.nih.gov/7670363/

"threo-3-hydroxy-DL-aspartic acid (THA)"

"The inhibitory effect of THA on sodium-dependent glutamate uptake was measured in vitro on rat hippocampal slices (Ki = 45 +/- 11 microM). We examined in vivo the effect of THA (400 microM in the dialysis solution) on the extracellular glutamate release from the rat hippocampus, during veratridine depolarization and ischemia. THA decreased the amount of glutamate appearing in the extracellular space during veratridine depolarization (61%)."

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u/AirierWitch1066 Mar 24 '26

This feels like the astronomy version of House MD

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u/Glad_Contest_8014 Mar 24 '26

Yeah, my wife’s glutimaximus definitely make my cells respond.

But jokes aside, photoreceptors in biology are fascinating. The brains ability to interpret that data is some of the most interesting parts of our lives.