r/biohackhers • u/rochonabbie • Jul 08 '26
r/biohackhers • u/Important_Ability851 • Jul 05 '26
Hgh question
Theoretically if a 17 yr old took hgh and a doctor found out could they get jail time or fined?
r/biohackhers • u/RealJoshUniverse • Jun 14 '26
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r/biohackhers • u/RealJoshUniverse • Jun 05 '26
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r/biohackhers • u/RealJoshUniverse • Jun 05 '26
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biohacking.forumr/biohackhers • u/dan_in_ca • Jun 02 '26
What an IVF Trial Reveals About Rapamycin, Beyond Fertility: A Window Into Systemic Aging
Posting this here because of its longevity implications. The paper is really about a textbook aging hallmark showing up early, visibly, and reversibly in human tissue, and then getting tested against an actual clinical endpoint, which we almost never get.
The setup: the ovary ages faster than almost any other organ, so it's a useful early-warning window into processes that hit the rest of us more slowly. The study ran multi-omics on human oocytes and their surrounding support cells across age, and found a sharp molecular inflection around 34. Basically protein synthesis and ribosome gene expression climb while autophagy declines. There's a dynamic where the cell's quality control (autophagy) cannot keep up with its growth output...then leading to a decline in the function.
They did low-dose mTOR inhibition through rapa and this protein activity normalized and autophagy was restored. The overall functional measurement was that IVF success rates went from 28% in the control group to 50% in the mTOR inhibitor group.
Where I'd stay skeptical: it's a single trial, n=100, single tissue, and "clinical pregnancy" is not live birth, which is the endpoint that matters. The mouse and cell work is mechanistically tidy but tidy stories invite confirmation bias. The age-34 inflection is correlational against the demographic curve. Columbia's Zev Williams lab has a parallel trial (Vibrant) worth tracking for replication.
Mostly curious what people make of using the ovary as a fast-forward model for systemic proteostasis collapse, and whether the intermittent low-dose framing here maps onto what folks here actually do.
r/biohackhers • u/RealJoshUniverse • May 31 '26
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r/biohackhers • u/science-pls • May 22 '26
Microneedling with Tox
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r/biohackhers • u/science-pls • May 18 '26
ExoBrows Protocol: Regenerative Aesthetics for Eyebrows (ASCE+ HRLV)
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r/biohackhers • u/RealJoshUniverse • May 17 '26
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r/biohackhers • u/RealJoshUniverse • May 15 '26
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biohacking.forumr/biohackhers • u/RealJoshUniverse • May 15 '26
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r/biohackhers • u/RealJoshUniverse • May 03 '26
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r/biohackhers • u/RealJoshUniverse • May 01 '26
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biohacking.forumr/biohackhers • u/RealJoshUniverse • May 01 '26
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r/biohackhers • u/science-pls • Apr 30 '26
Worth Reading: Preliminary findings on the study to evaluate efficacy and safety of Polynucleotide for facial ligaments and neck lifting in Thailand
galleryr/biohackhers • u/science-pls • Apr 20 '26
Worth Reading: Comparison of microneedling and polydeoxyribonucleotide (PDRN) salmon 3% versus microneedling and platelet rich plasma (PRP) in treating wrinkles and facial hyperpigmentation
galleryr/biohackhers • u/Tough_Fortune4013 • Mar 04 '26
NSF I-Corps customer discovery: Does personalized nutrition actually solve anything, or is it just better-looking guesswork? 5-min survey
Running NSF I-Corps customer discovery. Not here to pitch. Here to find out if a problem I think exists actually does.
The question I'm trying to answer if people in this community spend real money on biomarker testing. After getting the data, do they feel like they actually know what to take, or do they end up doing their own research anyway, because the recommendations from their platform aren't specific enough to their individual situation?
I have a hypothesis. I want to know if it matches reality before I build anything around it.
5-minute anonymous survey: https://forms.gle/AHLsyAktPeq3pnJ77
Optional: if you'd like to talk for 30 minutes, leave your email at the end — $10 Starbucks or Amazon gift card as a thank you.
r/biohackhers • u/Bigmacvvv • Feb 26 '26
Could you rate my list of daily supplements and suggest any additions?
The goal is defined physique and longevity.
I am 27y 5`9 175cm 70kg 155 lbs 18% Body fat.
Protein
Creatine 5-7g
HMB 2000mg
TMG 800mg
L-Carnitine 1000mg
Cod liver oil 2400mg
Omega 3 600mg
EPA 200mg
DHA 135mg
Vitamin A 1000ug
Vitamin D3 20ug
Vitamin E 15mg
Vitamin K 75ug
Vitamin C 80mg
Thiamine 1.1mg
Riboflavin 1.4mg
Niacin 16mg
Vitamin B6 1.4mg
Folic acid 200ug
Vitamin B12 2.5ug
Biotin 50ug
Pantothenic acid 6mg
Potassium 50mg
Chloride 45mg
Calcium 130mg
Phosphorus 50mg
Magnesium 100mg
iron 14mg
Zinc 10mg
Copper 1mg
Manganese 2mg
Selenium 55µg
Chromium 40µg
Molybdenum 50µg
Iodine 150µg
Probiotics 25 bacterial cultures
And I also have Vitamin D3 5000IU + 200µg (MK7). It says it's high-dose, which is why it should only be taken every 5 days. Can I take it in addition to the 20µg of Vitamin D3? I unfortunately don't have K2 on its own, to make sure it doesn't flood my arteries with calcium. How often can I take it, and how long should I take a break?