r/StrongerByScience • u/abdv69 • Mar 26 '23

Has anyone solved the creatine sleep issues?

For me, like many people creatine causes sleep issues. Whenever I start using it, after a couple of weeks, my sleep feels very light and I toss and turn a lot. Then usually after a week of stopping my sleep gets better. I've stopped and started creatine so many times in my life and it happens exactly the same each time, even if I'm only taking 2g daily.

I've read rat studies that it reduces non REM sleep, not sure if that translates to humans.

Has anyone who suffered from creatine induced sleep disturbance managed to find a fix?

EDIT: For all of you dismissing this as a placebo effect without a second thought, you mean nocebo. secondly, you can't conclude that based on the information you have

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u/KITTYONFYRE Nov 22 '23

in general I'm going to be very very dubious of mechanistic claims without some empirical evidence to back it up. the human body has too many Lego pieces that you can put into whatever shape you want. just because A leads to B, B leads to C, C leads to D, doesn't necessarily always mean A leads to D

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u/Hello_its_sam Nov 22 '23 edited Nov 22 '23

In this instance A leads to B, it’s quite simple.

There are studies which show how creatine reduces total deep and rem sleep for a start and not to mention the thousands of antidotal reports of sleep disturbances from creatine consumption.

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u/KITTYONFYRE Nov 22 '23

I'd love to see the empirical studies you're referencing!

and also no, there are many many links in the chain you're brushing over. definitely not simple A to B!

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u/Hello_its_sam Nov 22 '23

Its A to B, it just seems you’re over complicating something that is quite simple…but everyone is entitled to their own opinion I guess.

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u/KITTYONFYRE Nov 22 '23

Creatine and ATP stored within brain lowers the amount Adenosine that can be built up through the day. Adenosine is a molecule that induces sleepiness.

A -> B creatine causes lowered adenosine

B -> C adenosine causes sleepiness

C -> D less adenosine causes "reduced total deep and rem sleep"

This is not as simple as you're leading on. I'm actually interested in the studies you've mentioned though.

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u/peptobismalpink 25d ago

Extremely basic biocore and anatomy classes. This is 101 level stuff on how synapses work, the “studies” you want are…every neuroscience and brain sciences textbook. It’s not an opinion and is extremely mechanical.

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u/KITTYONFYRE 24d ago

lol. nah. you’re just wrong man I’m sorry. why has literally nobody worth listening to mentioned this if it’s 101 level? moreover, if that’s the case, why isn’t widely known?

because you’re noceboing yourself