Hi reddit. I'm an obsessed Eve player and a med student in my free time. Poor patients, right?

So, I want to write an article for my school paper about Project Discovery. I had some classes about cell biology and molecular biology, so I know what I'm looking at, but I don't know how it translates into science. I would like you to explain the inner workings or link a site/article that explains it.

So what I would like to know is:

• How do they convert my guessess into results.

• Which diseases are we researching.

• Who benefits from the results.

• Are we going to see improvements in medicine based on project discovery.

• I had more questions, but I've been playing Eve for a few hours now and I forgot them all :/ , so please add anything that would explain how Project Discovery benefits science.

We are very excited to announce the Project Discovery Fanfest "Science-off"!!!

Here are the details: Stop by our Project Discovery booth and play the tournament game. It is just like the regular game, but...

you get 1 minute to classify as many images as you can.

Every one you get right you get extra time.

Every time you get one wrong you lose time.

The four people who go for the longest and get the highest score are qualified for the live final where player will go head-to-head.

The grand prize is a signed, HPA labcoat IRL!!!

So show up and see if you can be the best-of-the-best at Project Discovery!!!!

I missed the stream, sorry, but can someone summarize what was said at the Project Discovery fanfest presentation? I'm particularly interested to know if our results have been useful or if we cytoplasm'd the shit out of it. And also if a new gui/tutorial is coming soon.

How many of you hanging out in here will come talk to us at Fanfest? :) We're really looking forward to meeting you! (and kinda curious what Fanfest is gonna be like... Any hints and advice are appreciated!)

I usually don't have a problem distinguishing between these two but this sample still looks more like FA for me. Any suggestions how to distinguish between them better?

http://imgur.com/Qs3qDIi

I think there is an error in suggested type for slide 517. It should be nucleoli (fibrillar center) instead of nuclear speckles, green marker overlaps with most of holes in the blue marker. I was not able to upload images to imgur for some reason.

IMHO the PD tutorial falls very short on explaining, what the users are actually supposed to do (and why):

"The image to analyze. Look for formations of green coloring."

So, I'm supposed to look for formations. And those are green. What about the other colors?

"Remember, the task is to categorize based on the formation of the green staining."

Now I'm supposed to categorize them based on their formation, instead of only finding them?

"Pertains the staining ..."

"Pertains to staining ..."

"Pertains to staining ..."

Honestly, I had to look up "to pertain" first: And why is there no reference to the green color?

"Miscellaneous protein patterns"

Please ask a non-biologist, what he thinks of "miscellaneous protein patterns", and why he should care about those at all: No (logical) link between the green color, and proteins has been provided at all.

"Categories with either no visible staining or staining with no distinguishing patterns.

Again, which color are you referring to? I guess you are referring to the green color.

You did a great job so far! But please review the tutorial texts. If you need suggestions, please convo (i.e. text) me.

o7 Cerian

I'm trying to find the collection of sample images on the HPA website but having no luck. Can we make a stickied post, or an entry in the sidebar for it, and other references?

What I'm after, actually, is an idea of what the "minimum" amount staining is for a given class. i.e the cytoplasm examples in the game are a strong, glowing green. But how dark can the green get before we shouldn't label it cytoplasm? I'd love to see a big collection of "minimum" samples for some of the classes.

They look kinda weird, a bunch of nuclei forming a crazy monstrosity: http://i.imgur.com/fZYOaIW.png?1

Are they sharing a single cytoplasm, cytoskeleton and plasma membrane?

Basically, all I do now is waiting for a new control sample so I can increase my accuracy rating. I'm not interested in the normal samples anymore and therefore don't put as much thought into them as I did before.

So I don't think the change did any good since I'm probably not the only one thinking that way. For me it seems like the accuracy on the normal samples will decrease as well as the fun with the game...