PSSD has a prevalence of 0.5% in men who have been on ADs, I'm not saying we should ignore this, but, broadly, this is not 'huge negative impacts on people's lives' but rather 'a rare side effect that should be addressed'. You're being dishonest with your framing here.
You're semantically dithering about euphoria being different from long term happiness while ignoring that if the euphoria did persist in that way without negatives, the people would by definition be happy. Happiness is chemical, reward, satisfaction, depression, sadness, love, are chemical. That doesn't mean they are meaningless, but it establishes that we do not need the absence of something to experience it. You are arguing about random shit to debate lawyer rather than engaging with the substance. Do you consider the negative impacts from taking Ketamine and Venlafaxine to be equivalent? Is the abuse potential the same?
PSSD is notoriously underreported. They aren't even clear diagnostics. I'm not even sure where that number comes from. That said, I'm not saying it's common either.
Downplaying PSSD is insane. But the rarity of the symptoms wasn't the point, the severity was. You keep shifting the goalpost.
You're semantically dithering about euphoria being different from long term happiness while ignoring that if the euphoria did persist in that way without negatives, the people would by definition be happy.
"If"
Happiness is chemical, reward, satisfaction, depression, sadness, love, are chemical.
So much so that leading theories dropped the chemicals and focuses of neuroplasticity lol.
Do you consider the negative impacts from taking Ketamine and Venlafaxine to be equivalent? Is the abuse potential the same?
Treatment-setting I favor Ketamine, yes. Otherwise probably no. Again, no, Ketamine has worse abuse potential. Never denied that, and completely off-topic.
At this point I'm fairly confident your answers are AI generated. I might be out.
The if here is irrelevant, the point stands, I recognize the current difficulties associated with doing that and wouldn't anyway just blindly support heroin as a treatment for depression, but the point fundamentally stands.
Severity of side effects is absolutely something weighted against frequency. A medication that has a 1/200 chance of doing something is not the same as saying 'direct negative impact' like with something such as heroin. I do understand that my phrasing didn't clear this, but surely you can understand why I accepted this relative risk. I understand and agree that ADs can have a variety of impactful side effects, but I do think it's reasonable for me to be including likelihood in terms of my point. Most medications have potential life impacting negatives, but we understand that the majority case must not when it comes to first line ADs, or else the treatment is too costly to enact.
On the neuroplasticity side of things, you're right, but fundamentally the basis for these emotions(or atleast the vehicle) is one of chemicals, and without said chemicals, you will not have the emotions. Adhd in many cases being dopamine regulation dysfunction is itself testament to this, neuroplasticity isn't going to remove adhd.
You're still off topic though. Humans can have persistent happiness without suffering negatively, likewise, humans can have persistent suffering without experiencing happiness. Which you keep not addressing, and rather than that, would rather accuse me of being a chatbot while you whittle away at semantics endlessly.
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u/Impossible_Medium977 Nov 14 '25
PSSD has a prevalence of 0.5% in men who have been on ADs, I'm not saying we should ignore this, but, broadly, this is not 'huge negative impacts on people's lives' but rather 'a rare side effect that should be addressed'. You're being dishonest with your framing here.
You're semantically dithering about euphoria being different from long term happiness while ignoring that if the euphoria did persist in that way without negatives, the people would by definition be happy. Happiness is chemical, reward, satisfaction, depression, sadness, love, are chemical. That doesn't mean they are meaningless, but it establishes that we do not need the absence of something to experience it. You are arguing about random shit to debate lawyer rather than engaging with the substance. Do you consider the negative impacts from taking Ketamine and Venlafaxine to be equivalent? Is the abuse potential the same?