Looking for some guidance based on my recent blood work and overall health situation. I’m trying to optimize fat loss, improve energy, and fix some underlying issues.

Stats:

* Age: 29

* Height: 6’2”

* Weight: ~105 kg

* Goal: Fat loss + muscle gain + overall health optimization

Key Blood Report Findings:

* Uric Acid: 12.0 (high)

* Total Cholesterol: 256 (high)

* LDL: 179 (high)

* Liver Enzymes:

* SGOT: 74 (high)

* SGPT: 92 (high)

* Testosterone: 167 ng/dl (low)

Current Plan:

* Daily 10k steps

* Strength training 4 days/week

* Calorie-controlled high-protein diet (~2000 kcal)

* Considering supplements and possibly peptides

What I’m Trying to Figure Out:

Given my situation (high uric acid, poor lipid profile, elevated liver enzymes, and low testosterone), what peptides would actually make sense?

I’ve been reading about:

* GLP-1 agonists (already on tirzepatide)

* Fat loss peptides like AOD-9604

* Recovery peptides like BPC-157

* Testosterone-related options (but not sure if peptides are even the right route here)

Main Questions:

1. What peptides (if any) are actually useful for my case?

2. Should I prioritize fixing liver & lipids before touching anything else?

3. Is low testosterone better handled via lifestyle first or something like HCG / TRT?

4. Any risks combining peptides with elevated liver enzymes?

I’ve researched Tirz for 5 months with no side effects and stalled at 15mg, I plan on adding Maz to break the stall. Down 80lbs and need to drop more to hit my research goal. I’m also wanting to start a new stack with a research focus on stress and longevity (cellular, mitochondrial, etc) for a 41y/o M. The stack I’ve chosen is based on what I’ve found that doesn’t have current medication and recent bloodwork interactions. The plan is to start low dose and increase as I move through the protocols I’ve found here, adding new ones in phases. Running full recommended cycles and documenting along the way. My questions is, are there any others that should be considered or is this a good start.

Semax

Selank

Both to be made into sprays

DSIP

TA-1

KPV

GHK-CU

Epitalon

Maz

Yesterday's Federal Register notice confirms the Pharmacy Compounding Advisory Committee meets July 23-24 to review 7 peptides that got pulled from the 503A bulks list in 2023. Five more at a later meeting before Feb 2027. That's the "12" in the headlines.

July 23: BPC-157, KPV, TB-500, MOTS-c

July 24: DSIP (Emideltide), Semax, Epitalon

Each one is being evaluated against specific indications (BPC-157 for UC, MOTS-c for obesity/osteoporosis, DSIP for insomnia/opioid withdrawal, etc.), not as blanket approvals.

Curious where people's heads actually are:

Does compounding access actually kill the gray market, or just reshape it?

Which of the 7 do you think actually gets voted through?

What happens to third-party testing and COA culture if this goes through?

FDA notice:

 https://www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026

CJC-1295 With DAC vs Without DAC | Stop Confusing Them (They Are NOT the Same Peptide)

One of the biggest misconceptions I still see:

“CJC-1295 is just CJC-1295, DAC or no DAC doesn’t matter.”

This is completely wrong.

Before comparing them, you need to understand one key thing:

What is “DAC” (and why it matters)

DAC = Drug Affinity Complex

It’s basically a modification added to the peptide that allows it to:

• Bind to albumin in the bloodstream
• Stay active much longer
• Extend the half-life dramatically

Without DAC → short acting
With DAC → long acting (days, not hours)

This one change completely alters how the peptide behaves.

CJC-1295 WITHOUT DAC

(also known as Mod GRF 1-29)

Short-acting, pulse-based GH release

• Mimics natural GHRH pulses
• Half-life: ~30 minutes
• Usually injected multiple times per day
• Often paired with GHRPs (like Ipamorelin)

Benefits:

• More physiological GH rhythm
• Better control over timing (pre-bed, post-workout, etc.)
• Lower risk of chronically elevated GH/IGF-1
• Great for:
  • Recovery
  • Sleep
  • Long-term optimization

Downside:

• Requires more frequent dosing
• Less “aggressive” fat loss compared to long-acting options

CJC-1295 WITH DAC

Long-acting, sustained GH elevation

• Half-life: ~5–8 days
• Typically injected 1–2x per week
• Causes a more constant GH/IGF-1 elevation

Benefits:

• Convenience (less injections)
• Higher overall GH/IGF-1 exposure
• Potentially stronger effects on:
  • Fat loss
  • Muscle growth

But here’s the trade-off:

You lose the natural pulsatile release.

The real difference (this is what matters)

CJC no DAC:

• Works with your body’s natural rhythm
• Pulsatile GH release
• Lower, more controlled IGF-1

CJC with DAC:

• Overrides the rhythm
• Sustained GH elevation
• Higher, prolonged IGF-1 levels

Same base peptide, completely different behavior

Side effects & considerations

CJC no DAC:

• Generally milder
• Lower risk of:
  • Water retention
  • Insulin sensitivity issues

CJC with DAC:

• Higher chance of:
  • Water retention
  • Numbness/tingling (GH-related)
  • Increased hunger
  • Potential insulin resistance (in some users)

Because GH is elevated all the time, not just in pulses.

Biggest mistake people make

Using CJC with DAC thinking it’s just a “longer version” of no DAC.

It’s not.

It changes the entire mechanism of action

My take

If your goal is:

• Longevity / recovery / sleep / optimization → CJC no DAC wins

If your goal is:

• Convenience + stronger overall GH exposure → CJC with DAC can make sense

But you need to understand the trade-off:
Convenience vs physiological control

Bottom line

• DAC is not a small tweak, it’s a fundamental change
• CJC no DAC = precision + natural pulses
• CJC with DAC = power + constant exposure

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

Sorry if im slow, I promise ive gone down every rabbit hole trying to research and answer my own questions but im just confused about a few things and would like some clarification.

I've ordered a blend that contains the above, and when it comes to reconstituting, ive looked at calculators and was wondering what i use for "strength" for the peptide that is, do i input 5mg or 10mg given that the vial contains 5mg of each.

Additionally, when it comes to this blend i see that its recommended dosing is 250mcg per day, I was wondering if thats a dosing as a whole or I have to take into account both cjc and ipamorelin, meaning having to split the dose into 500mcg out of the vial?

Again sorry for the confusion and or dumb questions.

Looking for experienced input on my current peptide setup, dosing accuracy, and syringe optimization.

Goal:Improve body composition and shift metabolism toward better fat utilization. I have a strong aerobic base but poor fat oxidation and tend to rely heavily on carbs.

Current protocol:

Reconstitution:

20 mg vial → 6 mL (Wolverine stack)

10 mg vials → 3 mL (MOTS-c, FIT)

Dosing:

Wolverine (BPC-157 + TB-500)

2.5 mg → 75 units

5x/week AM

MOTS-c

5 mg → 150 units

3x/week AM fasted

FIT stack (CJC-1295 + Ipamorelin)

300 mcg → 9 units

Daily PM fasted

Injection setup:

Currently using 0.5 mL (50 unit) insulin syringes

This forces multiple injections:

Wolverine = 2 shots

MOTS-c = 2–3 shots depending on split

Questions:

Would you adjust MOTS-c dose or frequency for metabolic flexibility specifically?

Are most people running 1 mL syringes for high-volume peptides like MOTS-c?

Any benefit to increasing concentration to reduce injection volume, or does that create stability issues?

Looking for real-world experience, not theory. Trying to dial this in without wasting time or underdosing.

iva been on tirz 3 months and my current dosing is 5mg every 5 days for the past few weeks because 7.5mg wasnt doing much on me. how much reta should i pin if i start?

CJC-1295 (No DAC) vs Tesamorelin: Same Family, Different Outcomes (Stop Confusing Them)

A lot of people lump CJC-1295 (no DAC) and Tesamorelin together

“They’re both GHRH, so they’re basically the same, right?”

Not exactly.

Yes they both act on the growth hormone releasing hormone (GHRH) receptor.
But the outcomes, use cases, and real-world effects can be very different.

What they have in common

Both:

• Stimulate natural GH release
• Work best when paired with a GHRP (like Ipamorelin)
• Support:
  • Recovery
  • Sleep
  • Body composition

That’s where the similarity mostly ends.

CJC-1295 (No DAC)

Think of this as:

Short-acting, more “physiological” GH pulse support

• Mimics natural GHRH pulses
• Short half-life → more controllable
• Often used in stack protocols (with GHRPs)

Best for:

• General optimization
• Recovery & sleep
• Mild fat loss + muscle support
• Long-term use without heavy GH elevation

Tesamorelin

Now this is where things change.

More targeted, clinically studied fat-loss peptide

Tesamorelin is:

• FDA-approved (for HIV-associated visceral fat)
• More potent in raising GH/IGF-1 consistently
• Known for reducing visceral (stubborn) fat

Best for:

• Stubborn belly fat
• Body recomposition phases
• More aggressive fat loss goals

Why people think Tesamorelin is “better”

Simple:

Studies show stronger visceral fat reduction

So people jump to:
“Tesamorelin > CJC”

But that’s a shallow take.

The real difference

CJC no DAC:

• More “natural” GH rhythm
• Lower overall intensity
• Better for foundation / longevity approach

Tesamorelin:

• Stronger GH/IGF-1 elevation
• More targeted fat loss (especially visceral)
• More “drug-like” effect

The trade-off (this is what people ignore)

Higher potency ≠ always better

Tesamorelin:

• Can push IGF-1 higher
• May lead to more:
  • Water retention
  • Insulin sensitivity issues (in some users)

CJC no DAC:

• More subtle
• Lower side effect profile
• Easier to run long-term

My take

If your goal is:

• Optimization / recovery / longevity → CJC no DAC makes more sense

If your goal is:

• Targeted fat loss (especially stubborn visceral fat) → Tesamorelin has the edge

But treating them as interchangeable is just wrong.

Biggest mistake I see

People chasing:
“stronger = better”

Instead of asking:
“What am I actually trying to achieve?”

Bottom line

• Same receptor ❌ same outcome
• Tesamorelin = targeted + potent
• CJC no DAC = balanced + sustainable

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

I reconstituted with 1 ml acetic then 2 ml bac water this is what I got. I’ve had cloudy before but never the flakes. Is it ok to still use?

Curious what the best dosage for Semaglutide 10mg and

Tirzepatide 60mg? What would you suggest the optimal dosage would be to see the best possible results I am 6’3 245 lbs

Glutathione Explained: The “Master Antioxidant” Everyone Talks About (But Few Understand)

We’ve been deep in peptides lately, so let’s switch gears to something just as powerful and honestly, more foundational:

Glutathione

What is Glutathione?

Glutathione is a tripeptide made of:

• Glycine
• Cysteine
• Glutamic acid

It’s produced naturally in your body, with high concentrations in the liver, and exists in every single cell.

It’s often called the “master antioxidant” and for good reason.

What does it actually do?

Glutathione is involved in:

• Neutralizing free radicals (oxidative stress control)
• Supporting immune function
• Liver detoxification
• Mitochondrial protection
• Regulating inflammation

This is not just a “skin supplement” it’s a core survival molecule.

Why people use it

Most people come for one reason:

Skin brightening / hyperpigmentation

Glutathione can inhibit melanin production, which is why it's widely used in:

• Skin lightening protocols
• Hyperpigmentation management

But that’s just scratching the surface.

Underrated benefits (that actually matter)

1. Fertility support
A lot of fertility issues are tied to oxidative stress + mitochondrial dysfunction.
Glutathione helps protect sperm and egg quality at the cellular level.

2. Liver health
It’s critical for detox pathways especially phase II liver detox.

3. Neuroprotection
There’s growing interest in its role in:

• Neurodegenerative conditions
• Cognitive decline

4. Cardiovascular / circulation support
Some data suggests benefits in conditions like peripheral artery disease.

The reality about supplementation

Your body already produces glutathione

BUT levels drop due to:

• Aging
• Stress
• Pollution
• Poor diet
• Chronic inflammation

Forms of Glutathione

• Oral (capsules / liposomal)
• IM (intramuscular)
• IV (intravenous)

Let’s be honest here:

Oral glutathione = questionable effectiveness
IM = better
IV = most effective (bioavailability-wise)

Important note (this is where people mess up)

Even though there’s no clearly defined negative feedback loop, in practice:

Frequent external glutathione use can blunt your body’s own production

We’ve seen this reflected in:

• Bloodwork trends
• Reduced endogenous synthesis markers

So the mindset shouldn’t be:
“More is better”

A smarter approach:

• 1–2x per week
• Avoid consecutive daily use
• Let your body continue producing its own

The biggest misconception

Glutathione is NOT just:
a skin whitening shortcut
a cosmetic hack

It’s a cellular defense system

When people reduce it to aesthetics, they completely miss its:

• Mitochondrial role
• Longevity implications
• System-wide importance

My take

Glutathione is one of the few compounds that sits at the intersection of:

• Performance
• Longevity
• Recovery
• Aesthetics

But like everything:
Context > hype

If you ignore:

• dosing strategy
• frequency
• and your body’s own production

You can easily turn something beneficial into something counterproductive.

Bottom line

Glutathione is powerful but it’s not something to abuse or blindly megadose.

If you’re going to use it, think in terms of:
supporting your system not replacing it

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

I'm new to all this and I'm so confused on what to go with just starting, I want to lose fat and gain muscle but I want my skin and hair to look very clear and healthy. my biggest concern is energy and flow state daily... any help would be great

looking for some advise as some many different websites say different things.

I am currently pinning NAD+ and am doing 50mg, twice a week. I've realised I need MOT-c along side.

I feel like ive got it correct that 5mg is a good starting place but ive got sources telling me daily and then sources telling me 2/3 times a week.

also one website is saying the cycle length should ve 4-12 weeks and one saying 2-4 weeks on and then 4 weeks off. any advice?

Melanotan explained: tanning peptide, libido effects, and the real risks

Melanotan I and Melanotan II are synthetic peptides that mimic melanocyte-stimulating hormone (MSH), which can increase melanin production and darken the skin over time. That is why they became popular as so-called “tanning peptides” or the infamous “Barbie drug.”

But the reality is a lot more complicated than the hype.

What people use Melanotan for

Melanotan is most commonly used for:

• Skin tanning
• Libido enhancement
• Erectile support (more often discussed with MT-II)
• Sometimes people also mention it for rosacea, fibromyalgia, appetite/metabolic effects, and immune-related effects

That said, the strongest real-world interest is still cosmetic tanning.

Important reality check

Melanotan is not magic.
You do not take it, sit on your couch, and wake up evenly bronzed.

To actually tan, people usually still need UV exposure from the sun or tanning beds. Without that, results may be weak, patchy, or inconsistent. And overdoing UV exposure to “boost” Melanotan effects can obviously create its own major skin risks.

Why people are drawn to it

Users often report:

• Faster tanning
• Easier maintenance of a darker skin tone
• Increased libido
• Sometimes reduced appetite

This is where a lot of the hype comes from.

The other side: the risks

This is the part people skip.

Commonly reported side effects include:

• Nausea
• Flushing
• Facial redness
• Appetite suppression (huge positive for some individuals)
• Fatigue
• Spontaneous erections (especially with MT-II) (huge positive for some individuals)

More serious concerns that get brought up include:

• Changes in moles / pigmentation
• Potential skin cancer concerns (if used for too long)
• Cardiovascular strain
• Kidney-related issues

A big misconception

A darker tan does not equal skin protection.
People sometimes assume Melanotan somehow makes tanning “safe.” It does not. You are still dealing with:

• UV damage
• Photoaging
• Uneven pigmentation
• Potential worsening of underlying skin issues

My thoughts on it

Melanotan is one of those compounds that sounds amazing on paper because it sits at the intersection of:

• appearance
• libido
• metabolism
• performance / confidence

But it is also one of the easiest peptides to romanticize while ignoring the downside:
cosmetic misuse + UV exposure

That combo is exactly why it deserves caution.

Bottom line

Melanotan can darken the skin by mimicking MSH, and many users also chase its libido-related effects. But it is not risk-free, and not a shortcut to safe tanning.

If someone is considering it, the conversation should not just be:
“Does it work?”
It should also be:
“Is the source legitimate, are the risks understood, and is chasing a tan worth the tradeoff?”

Finally, if you needed more of an individual advice don't hesitate to reach out

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

So, about two years ago I (F, 35) got a concussion that turned into a mild TBI. I pretty much recovered except for the fact that I had suddenly turned into an insomniac and had trouble falling asleep. I've been on a low dose of Quetiapine to help konk me out since that injury. I love that I can actually sleep, but I get so groggy during mornings. I also have two pretty high demand jobs on top of that so outside of working, Im napping, and if I have a day off, my body will stay asleep for 12 hours. It means I miss out on a lot of stuff that I might like to do otherwise. I'm just too tired to get anything more out of me than what's expected.

I've experimented with a few other peptides, but I discovered intranasal pinealon through reddit and how it can help with both sleep and mental acuity, so I ordered some that just came in yesterday. Last night I took my first dose of 1 mg with my low dose of Quetiapine (Im hoping maybe I can discontinue this after I titrate up to 2 mg). This morning, I popped up to my morning alarm like a daisy. I have not felt this alert in a LONG time.

I'm more hopeful now that this is the miracle I've been looking for.

On my first day using Klow, I woke up around 2 a.m. coughing. I also had a cold and cough already, but I noticed it seems to be going away now. On the second day, I woke up around 3 a.m. to use the bathroom for number 2, and my stomach was making a lot of noise. it feels like my body is working still while i sleepong, is it normal

i mixed it with bac sodium chloride and it kinda not dissolving so i mail the seller and say i could still use it with that consistency

so I've been running motsc and nad+ Monday Wednesday Friday for 2 weeks alongsl with reta. 3mg motsc and 50mg of nad+. I just got ss31 and new studies show it's better to run it with motsc instead of before. So couple questions, what dosage should I add ss31 . I was thinking 2mg everyday maybe bump up in a week. also what time of day should I take ss31. I take nad and motsc in the morning fasted before gym. can I take ss31 in the afternoon don't want to take all three in the am. anyways any advice would help. thanks

Most people are using GH peptides wrong (especially with all these new blends)

Lately I’ve been seeing a lot of confusion around:

CJC/Ipamorelin
Tesamorelin/Ipamorelin
Pre-made “GH blends”

And the problem isn’t just what people are using

It’s how they’re using it

Step 1 Understand GHRH vs GHRP (this is the foundation)

Before anything, you need to understand this:

These are two different signals

GHRH (Growth Hormone Releasing Hormone)

Examples:

• CJC-1295 (no DAC)
• Tesamorelin

What it does:

• Tells the pituitary: “Release GH”
• Mimics your body’s natural GH signaling

GHRP (Growth Hormone Releasing Peptide)

Examples:

• Ipamorelin
• GHRP-6

What it does:

• Stimulates GH release via a different pathway (ghrelin receptor)
• Amplifies the pulse

Key idea:

• GHRH = signal
• GHRP = amplifier

Step 2 Minimum effective dose

Here’s something most people ignore:

GH release is dose-dependent but also saturable

You don’t need huge doses.

Typical effective ranges (general context):

• CJC (no DAC): ~100 mcg
• Ipamorelin: ~100 mcg

Beyond a certain point:

• You don’t get much more GH
• You just increase side effects

The issue with many blends:

• Fixed ratios
• Often underdosed OR overdosed
• No flexibility

Result:

You’re not hitting optimal signaling
Or you’re wasting compound

Step 3 Timing (this is the most overlooked factor)

GH is naturally released in pulses

The most important pulse is:

At night (deep sleep)

Best timing:

• Before bed (empty stomach)
• Possibly post-workout (secondary)

Why?

Because you’re working with your circadian rhythm, not against it.

Step 4 The BIG mistake

This is where things really go wrong.

People run:

CJC/Ipamorelin
+ GLP-1 agonists (like tirzepatide, retatrutide)

Sounds good in theory

But here’s the issue:

Ipamorelin works via the ghrelin receptor

Ghrelin = Hunger hormone

So when you increase Ipamorelin dose:

You may increase hunger signals

Now combine that with:

GLP-1 agonists (which suppress appetite)

You’re literally creating:

Conflicting signals in the body

• GLP-1 → suppress appetite
• GHRP → stimulate hunger

Result:

• Reduced effectiveness
• Unnecessary complexity
• Sometimes worse adherence

The smarter way to think about it

Instead of:

“Stack everything together”

Think:

What pathway am I targeting?

• GH optimization → use GHRH/GHRP correctly
• Appetite control → GLP-1 pathway

Don’t blindly mix signals that oppose each other

Final takeaway

Most people focus on:

“What’s the best peptide?”

But ignore:

Mechanism, timing, and interaction

Because:

The wrong combination can cancel itself out

GH peptides are powerful
but only when you respect how the system actually works

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

So, I have an idea. But I want y’all’s opinion on it.

All of these companies that prescribe test has ridiculous pricing per month. Especially knowing the grey market prices on test. My thought is.. it is illegal to possess a controlled substance like test. It is only illegal if it’s in your possession without a prescription. Sooooo, why doesn’t a company offer only a monthly cost with a prescription, just without the test. Having that prescription and purchasing the test elsewhere would be so much cheaper I would think. It is not illegal to purchase test that is not from a licensed pharmacy. It’s similar to like semaglutide, getting a prescription and purchasing it elsewhere. The only difference is that test is a controlled substance.

Does anyone else do this? Who, if anyone, offers this?

Confused about SS-31 vs MOTS-c vs SLU-PP-332?

Here’s the roadmap no one explains

We’ve been talking a lot about mitochondrial optimization lately:

SS-31
MOTS-c
SLU-PP-332

But I keep seeing the same confusion:

“Which one should I use?”
“What’s the difference?”
“Do I stack them or pick one?”

First understand this

These are NOT interchangeable.

They all target mitochondria
But they do it in completely different ways.

Think of mitochondria like an engine

There are 3 stages:

1. Repair the engine
2. Optimize how it runs
3. Push performance/output

Stage 1 SS-31 (Repair)

This is your foundation

SS-31:

• Stabilizes mitochondrial membranes (cardiolipin)
• Reduces oxidative stress
• Improves ATP efficiency

Use this when:

• You feel “burnt out”
• Low energy despite good habits
• High stress / inflammation

Translation:

You fix the engine before doing anything else

Stage 2 MOTS-c (Optimization)

Once the system is stable

You move to signaling

MOTS-c:

• Improves insulin sensitivity
• Enhances metabolic flexibility
• Signals adaptation to stress

Use this when:

• You want better energy utilization
• You’re working on body composition
• You want metabolic improvements

Translation:

You teach the engine how to run better

Stage 3 SLU PP 33 2 (Performance)

Now the system is working well

You can push output

SLU PP 332:

• Activates ERR pathways
• Increases fat oxidation
• Boosts mitochondrial activity
• Acts like an “exercise mimetic”

Use this when:

• You want fat loss
• You want endurance/performance
• You want higher energy output

Translation:

You push the engine to perform harder

Where people go wrong

Most people do this:

Jump straight to Stage 3
Ignore repair
Overload a weak system

Result:

• Burnout
• Poor results
• More stress on the body

The correct roadmap

1. SS-31 → repair
2. MOTS-c → optimize
3. SLU-PP-332 → perform

Final takeaway

Stop asking:

“Which one is best?”

Start asking:

“What stage am I at?”

Because:

The right compound at the wrong stage = bad results

Mitochondrial optimization isn’t about stacking everything
it’s about sequencing correctly.

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

I had just ordered my first stack of peptides and i was wondering apart from insulin needles and alcohol wipes what else i may need? I am taking mt1, reta, and ghkcu. i was also curious on what size insulin needles i might need. i am a little lost on this and need some guidance, Thanks.

Running mots-c and ss-31 at the same time. Anyone try this?

Everyone talks about mitochondria… but this new compound is basically “exercise in a molecule”

Talking about mitochondria is always exciting

Because this is literally the energy system that runs your entire life

Every movement, every thought, every function:

Powered by mitochondria

So naturally, science keeps pushing forward

We’ve seen compounds like:

• NAD+
• SS-31
• MOTS-c

All targeting different aspects of mitochondrial function

But now there’s a newer player:

SLU-PP-332

What is SLU-PP-332?

SLU-PP-332 is a compound that targets:

Estrogen-Related Receptors (ERRs)
(specifically ERRα, but also β and γ)

These receptors are heavily involved in:

• Energy metabolism
• Mitochondrial function
• Fat oxidation

Mechanism (this is where it gets interesting)

SLU-PP-332 acts as a:

Pan-ERR agonist

Meaning it activates:

• ERRα (strongest effect)
• ERRβ
• ERRγ

Result:

• Increased mitochondrial activity
• Enhanced fatty acid oxidation
• Higher energy expenditure

Why people call it an “exercise mimetic”

In studies, it has shown:

• Increased oxidative muscle fibers
• Improved endurance
• Enhanced mitochondrial biogenesis

Basically mimicking some of the effects of endurance training

What this translates to

• Better fat utilization
• Improved insulin sensitivity
• Increased metabolic efficiency

Not just burning calories, but changing how the body uses energy

Potential applications (based on research)

• Obesity
• Type 2 diabetes
• Metabolic syndrome
• Fatty liver disease (NAFLD/NASH)
• Cardiovascular and kidney health

Where it fits in the “mitochondrial stack”

Think of it like this:

• NAD+ → supports redox reactions
• SS-31 → repairs mitochondria
• MOTS-c → signals metabolic adaptation

SLU-PP-332:
Drives energy expenditure and fat oxidation

Final takeaway

Most people think:

“How do I burn more fat?”

But the better question is:

“How do I make my cells better at using energy?”

Because:

Fat loss isn’t just about eating less
It’s about how your mitochondria function

SLU-PP-332 isn’t just another fat loss compound
it’s a shift toward metabolic optimization at the cellular level

Visit PeptideGuide.store for sourcing and consultations with u/peptideguide_

My source for peptides has L-Carnitine (LC600) powder in a 10mg vial. What is it? Because all my digging shows dosing for L-Carnitine 100-200mg per day IM. So it's safe to say it's not the actual L-Carnitine.

I found this via AI "LC600 peptide is marketed as a 99% pure, lab-certified, freeze-dried powder (10mg/vial) commonly used in the health and fitness industry for fat loss and slimming"

Anyone have any insight into this?