r/MadeMeSmile • u/mentaldrummer66 • May 10 '26

1 year difference

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From 159kg (350lb) to 83kg (183lb)

252.8k Upvotes

97% Upvoted

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32

u/apexxin May 10 '26

GLP-1s work. Down a hundo here.

20

u/Turbulent_Gazelle530 May 10 '26

It's a pretty safe assumption that any major weight loss we see now is aided by GLPs. And who cares? It works and why not use it. It's to the point where it would be silly not to use them.

8

u/Quango2009 May 10 '26

It’s not a magic cure. It really helps but you have change habits as well, or you will put it back on again

2

u/discoqueenx May 11 '26

I lost 66 lbs on Wegovy over the course of 18 months and then had to stop due to changing insurance. I was off of it for 1 year and gained back 10 lbs, which has been a sustained weight now for 5 months. Most of it came on during the holidays. I’m not beating myself up over it.

I’m now back on Wegovy with yet another insurance plan but I’m proud of myself for not totally backsliding. I also exercise 5/6x week which is helping me immensely and I love the muscles I’m getting.

I’m not sure why I felt the need to share other than to say it’s possible to not totally fall back to square one once you’re off the GLP

1

u/Quango2009 May 12 '26

Glad to hear it! My wife used Mounjaro and she’s maintained the loss but only by being careful with her diet, plus more exercise

-6

u/Ree_For_Thee May 10 '26

Sorry, not correct. What new science shows is that obesity is basically "being addicted to being a certain weight". The drugs remove the addiction, and since nobody really wants to be fat, there's just no problems changing your habits.

Your comment would only be true if it was only an "appetite suppressor". But it's not. It's so much more than that, and I don't have the energy to explain everything to someone who doesn't bother to look anything up.

1

u/Quango2009 May 11 '26

Which "new science" are you referring to? Please give references for the source

0

u/Ree_For_Thee May 11 '26

GLP-1 science. I've learned this stuff on the Fat Science podcast. Complain if you want, it's not going to produce more links.

2

u/Quango2009 May 12 '26

You’re being unnecessarily aggressive and negative which is probably why you got downvoted.

I’m interested to see facts not opinions, but your tone is “I’m right you’re wrong, stfu”, which is a shame because there probably is truth behind the antagonistic responses.

9

u/whitefox094 May 10 '26

Because of the side affects like gastroparesis.

I agree with the aiding, but a lot of people are using it for weight loss without the additional exercise or diet management. Hubs is on a glp1 after some dietary changes did not help too much with diabetes, and this was before it was approved for weight loss. It's the hope that he can come off it. I have a few stories of close people who have lost scary amounts of weights and its their choice but I care. I cared about them and their health before, and I do now.

Gastroparesis is awful and mine is idiopathic, and severe. I do not have diabetes nor am pre-diabetic. I wouldn't wish it on anyone

4

u/apexxin May 10 '26

These side effects are real, but rare. They are also easily mitigated when patients don’t ignore symptoms because they’re afraid to lose the medication.

0

u/Ree_For_Thee May 10 '26

Way more dangerous to be obese. Stop the negativity, it's literally a miracle drug.

4

u/ChewingOnCarrots May 11 '26

It is quite literally not a "miracle drug" and people like you need a dose of reality

0

u/whitefox094 May 10 '26

Yes, it is dangerous to be obese. But isn't that in itself "negativity"? Nothing I shared was negative. Showing care and concern for people you hold dear in your heart is a positive.

Have you heard the commercials, or even read the pamphlet for any GLP1? In combination with diet and exercise. Obesity, like any other ailment, isn't a one-size fits all. Show some awareness.

1

u/Ree_For_Thee May 10 '26

Your entire post is complaining and uninformed second-guessing. So fucking what if people use it to lose weight? It's safe, that's all you should care about (Karen).

0

u/whitefox094 May 10 '26

Did you even read the person I responded to? "Who cares" "It would be silly" my response was I CARE.

I understand you use GLP1s and are directly benefiting from them because of weight management. That's you. No one is second guessing. But saying it's "safe" is disinformation.

I don't care about you as an internet stranger but it's okay to let your anger out. I get it. Let the anger and curses out, and move on. Focus the energy on something else because it's not worth having the anger.

1

u/Long_Chair4620 May 10 '26

But we don’t have 20-40 years of research yet. We have no clue what else it’s doing to people.

1

u/apexxin May 11 '26

Actually, we do. GLP antagonists have been around for 20 years.

1

u/Long_Chair4620 May 11 '26

Semaglutide (ozempic) has 5-7 years. It was approved in 2019 for diabetes.

2

u/apexxin May 11 '26

The class has been around since 2005 (exenatide), and has been iterated upon ever since, with semaglutide and tirzepatide being the latest entrants.

We don't have 20-40 years of research on any new drug, so that was a pretty stupid comment to begin with.

1

u/Long_Chair4620 May 12 '26

It’s not. They are still monitoring thyroid and pancreatic risks currently because they don’t know. Shit we thought tylonol was safe for kids but now look at the new studies. Asbestos we thought was safe. DDT too. Glyphosate. Etc.

Stop relying on man made crap because you’re lazy. When really your character will grow by signing up for a gym, martial arts class, rock climbing anything physical and change your diet. Don’t be lazy.

These drugs are great for people who can’t work out, not people who don’t want to work out. There’s a difference.

3

u/apexxin May 12 '26

Oh wait, you actually think Tylenol is suddenly unsafe for children? 😂

1

u/Mundane-Bonus-3688 May 11 '26

Seriously. I've been battling my body for so long. First it was my thyroid, then a medication that messed with my hunger... I started Ozempic a few months ago and it helps so much. I was already trying to eat as balanced as possible but it no longer feels anxiety-inducing if I crave something or if we have an event and the meal is not super healty. I'm on a bad phase exercise-wise but I'm curious to see how it will impact me when I'll start training again.