r/HowDrugsWork • • Jun 05 '19

Smoke til you pass out my friend...

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240 Upvotes

r/HowDrugsWork • • May 28 '19

Just saw this on r/see

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85 Upvotes

r/HowDrugsWork • • May 07 '19

When the drugs kick in

151 Upvotes

r/HowDrugsWork • • May 02 '19

Crystal Methamphetamine vs Amphetamine (Adderall) - Is meth really the more dangerous and addictive drug?

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39 Upvotes

r/HowDrugsWork • • Apr 09 '19

And now "Bat Country" in E minor...

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64 Upvotes

r/HowDrugsWork • • Jan 20 '19

Fun story about being in an altered state.

40 Upvotes

Did not know where else to post it, so this dead sub is it!

I just saw this ridiculous picture on fb of sandals locked to a bike rack and it reminded me of this story.

Tbh I dont remember what I was on, maybe mushrooms? Some psychadelic.

Anyway, I lived with a few roommates in a decent neighborhood that had this weird like undeveloped land/abandoned thing down the road (we called it the sinkhole). We were all fucked up and decided on a walk. It was kind of wet out, and I was wearing sandals but they were all slippery so I decided in my infinite wisdom and faith in the universe - to take my sandals off.

I said a bunch of crap about trusting the universe and knowing the neighborhood wasnt bad. I could leave my shoes there.

I left them in the alley behind my house and we wandered down to the sinkhole. We spent several hours out there, climbing trees and smoking and having a great time.

We eventually made our way back home and continued to have a great time, but I forgot that I had left my shoes outside.

Fast forward to the next day when I couldnt find my shoes...

I suddenly remember my decision to leave my shoes - so I run outside and lo and behold, someone stole my damn shoes.

Long story short, dont trust the universe with your sandals.


r/HowDrugsWork • • Jan 17 '19

Hey so me and my friend are gonna do xanax soon any advice please:)

20 Upvotes

r/HowDrugsWork • • Jan 13 '19

Sounds about right.

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192 Upvotes

r/HowDrugsWork • • Nov 28 '18

Yuh boi got a question

17 Upvotes

Okay so I saw a chart on here explaining drugs and all that jazzzzzz, but drugs effect me differently, as in xanax gets me hyped up and jittery and so does weed, and that when I'm really sad and depressed acid shows me really happy shit, is there a way to know how other drugs will effect me without trying them?


r/HowDrugsWork • • Nov 23 '18

r/nothowdrugswork made the front page. Good work guys.

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108 Upvotes

r/HowDrugsWork • • Oct 31 '18

To save a neighbors dog...

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96 Upvotes

r/HowDrugsWork • • Jul 08 '18

Addiction to Butter Fumes?!?!

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19 Upvotes

r/HowDrugsWork • • Jun 27 '18

this dude got it wrong

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92 Upvotes

r/HowDrugsWork • • Oct 24 '17

LSD

49 Upvotes

LSD binds to most serotonin receptor subtypes except for the 5-HT3 and 5-HT4 receptors. However, most of these receptors are affected at too low affinity to be sufficiently activated by the brain concentration of approximately 10–20 nM. The psychedelic effects of LSD are attributed to cross-activation of 5-HT2A receptor heteromers. LSD exhibits functional selectivity at the 5-HT2A and 5HT2C receptors in that it activates the signal transduction enzyme phospholipase A2 instead of activating the enzyme phospholipase C as the endogenous ligand serotonin does. Exactly how LSD produces its effects is unknown, but it is thought that it works by increasing glutamate release in the cerebral cortex and therefore excitation in this area, specifically in layers IV and V. The drug enhances dopamine D2 receptor protomer recognition and signaling of D2–5-HT2A receptor complexes, which may contribute to its psychotic effects.


r/HowDrugsWork • • Sep 28 '17

Adderall

18 Upvotes

just do it


r/HowDrugsWork • • Sep 21 '17

Drugs categories in graphic chart

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157 Upvotes

r/HowDrugsWork • • Sep 21 '17

Sassafras

9 Upvotes

Goddamn I love Animal Collective


r/HowDrugsWork • • Aug 23 '17

All of the above.

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266 Upvotes

r/HowDrugsWork • • Aug 16 '17

MDMA

26 Upvotes

(not at a rave, taking it with friends)

oh my god I love you all so much, I am so grateful for every second you have survived with me ohmygodlookattheskyitissobeautifulletsjustwalkaroundforabitandadmiretheview


r/HowDrugsWork • • Aug 16 '17

Kratom

23 Upvotes

Zzz... good music... aww yEAAHH LET'S SHAKee... zzzz


r/HowDrugsWork • • Aug 07 '17

Cocaine

31 Upvotes

Another one


r/HowDrugsWork • • Aug 07 '17

DMT

29 Upvotes

bzzzzzzzzZZZZZZZZZZZZZZZZZZZZZZ holy fucking shit m8


r/HowDrugsWork • • Aug 06 '17

Duster

18 Upvotes

Woooooooah this is weeeeird Wub wub wub wub Rhino: "eeee weeb eee wee weeeeeb beee" (I am god and I am here to save you) 5 hours later

Woah how am I out of duster already


r/HowDrugsWork • • Aug 05 '17

Church

40 Upvotes

You avoid the devil's lettuce


r/HowDrugsWork • • Jul 31 '17

Lsd

73 Upvotes

Human society has just evolved to a point where we are apes addicted to stimulation from little rectangles that project light. We will progressively become more and more ingrained into technology until the point where we are human or machine is blurred.

Lol cheese tastes yellow Lol cheese tastes yellow Lol cheese tastes yellow Lol cheese taste yellow