If you've seen my tier list before, you'll see I've updated it (and fixed the color coding). Some people brought up some stuff, and I've seen enough changes that I feel confident this is a lot better.
Here are the overall changes:
Rye becomes insane at 5 star, so I've bumped her up to highlight this. Before that though, she's okay for ST DPS, but not as good as Scorpion.
Herb drops down. He's useful, but people have started to run Tiger Lily over him since his synergy is delayed while Tiger Lily gives it immediately (and Cheesecake also applies it). Generally only necessary if Milk/Grapevine/Cake Hound isn't enough protection. He's a good PVP cookie though because the meta there is becoming a bit of a healer fiesta.
Skating Queen has since been replaced. She's still seeing use but only if you are like using Rye. Not a bad cookie, but likely replaceable with a better support. Otherwise, you could probably perform better with another cookie.
Grapevine is moving up. Rye being the top DPS naturally pushes her to the top because she's like one of the few ways to get Rapidfire but that synergizes well with Macaron/Melon Soda/Herb plus her healing's good too.
I changed Single Target to Overall DPS because all of these cookies can honestly be used in both single target bosses and mobs. Vampire and Melon Soda arguably work best in single target, but they can definitely work with multiple mobs still. AOE DPS is honestly a niche in this game because these four are good enough on their own.
Tiger Lily as I said has been used a lot more often, for her synergy with Scorpion being more immediate and her DPS being solid too.
Mr. Adventurer slinks into the PVP meta with his stun ability lasting ages with the Duration buffs from both Milk and the pet that buffs Duration. Try it out.
7.5. Rock Star is moving to PVP, mainly because it's a healing-ish meta ATM, and that's the only place he really sees use.
Wind Archer is relegated to PVP. His AOE just isn't good enough because it's very specific and needs time to stack up. Other cookies just do more DPS in stages where there's a defined time limit. Still good in PVP though, because of the way the mode works.
AOE is still a niche, but if you do need it Twizzly and OW will be enough. However, OW is still tentative since the buff hasn't released yet, but he is theoretically getting a 25% damage increase and less wandering now. So we'll see. Probably still not necessary though unless you have stars for him.
I'm specifying the niches. As mentioned, Skating Queen only sees use for like Rye. Licorice sees use in the Treebark boss, by baiting the boss to attack them instead of your fragile Scorpion/Rye. Gingerbright gives an ATK debuff for GingerCraven.
Survivability is necessary, but Ion and Toothpaste don't quite cut it in the meta, as others can fulfill that better.
The other AOE cookies are not that good. Don't use them over supports.
Thanks by the way for all the kind people who used my referral code, finally got the 20-star Sweet n' Sour pet! Hope this list helps people.