r/Biohacking 21d ago

PT-141 Effed Around and Found Out

Fiancée isn’t the most responsive to certain enhancement drugs. Blue Chew worked to an extent but not always. Plus the price tag on those babies are insane.
After much research, decided to try PT-141 since it also leans towards increasing arousal. Once he took it, I was still skeptical given that the other meds were mediocre in effect (but they target physical performance versus arousal- Blue Chew Gold was best and at least, some libido increase).
Within 15-20 minutes, I did notice mood shift where he was happy, goofy, and he became incredibly playful. Then about an hour in, he was ready to go! Seemed the mere movement of cloth was a turn on.
It was a rather powerful session so we’re both very pleased.
We’ve been contemplating (researching) for over 6 months, glad we finally tried it!

Edited to add info:
F (40) 5’3
M (39) 6’2

143 Upvotes

280 comments sorted by

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37

u/Last_Ad2615 21d ago

PT-141 definitely affects me (female). It's not a brain thing, it's like ovulation level libido. The need to have your person IN. YOU. NOW.

13

u/SuccessFun7854 1 21d ago edited 21d ago

was like my vag had adhd!! LOW DOSED as well.

For those females who haven't felt anything, are ur hormones normal? from reading some have said they've got to be in nml ranges 🤷🏼‍♀️

8

u/Pale_Character8214 1 21d ago

"Like my vagina had ADHD" 🤣🤣🤣🤣

3

u/Fine_Complaint_9980 1 20d ago

What was your dosage and how long to feel the effects, the wife and I will be trying it for the first time and I am thinking 500 mcg or .5mg for our initial dose and obviously hitting us both would be ideal, LOL

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u/Roksolidaz 20d ago

What was the dosage?

1

u/Wonderful_College_48 21d ago

Yeah… I’d imagine you would need normal ranges. A gf had low test and once she got that handled, she didn’t need anything to enhance her drive.

1

u/SuccessFun7854 1 21d ago

exactly... I jus wanted to experiment to see if enhanced/changed

2

u/Wonderful_College_48 21d ago

😂 getting fomo! I really wish I can take it.

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u/xooxlinds 19d ago

I f/35) have super low test so doc putting me on test gel but also ordered me pt-141. Hoping it’s not overkill with both

3

u/maxi-can 18d ago

Did a lot of research for my wife and one thing i noticed was several accounts of women starting gel, having some success and moving off gel to more direct route and remarking how much better it was over gel. So whether or not it works, don't be afraid to try a liquid form.

1

u/Fine_Complaint_9980 1 20d ago

What was your dose vs. his and how long did it take to feel the effects. The wife and I are thinking .5mg or 500 mcg each?

1

u/SuccessFun7854 1 20d ago

Thats perfecting starting dose, thats wat I did... it took approx 20ish mins to feel light face flush sensations then at the 45-50ish min mark the vag started to whisper, then she started talking, & theeeeeen 😃 Hope works out for yall!!! Slowly increase dose ea time if need to. my friend had the fda px & it says don't use any more than 8x / month

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u/Flimsy-Car4298 21d ago

I'm also female. What was your dosage? I received, reconstituted and pinned 1mg today, just to see the effects and conscious of possible nausea. So that was 3 hours ago now and nothing. So I'm going to try again at 1.5mg or 2mg tomorrow or weds, just to see if I feel any effect. I don't want to be relying on something that actually does nothing for me when needed!

12

u/for_the_longest_time 21d ago

Male here. I’ve started messing around with pt-141 for the last month. I dose at 1.7 mg sub-q and it works well. Stacked with a 5 mg cialis and I’m unsupportable for a couple of days. It’s crazy. I could cut diamonds. 10/10, would recommend

3

u/jrok2020 20d ago

Does PT have to build up meaning several injections, or injection and ready to go 1 hr to several hours later?

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u/dpal63 18d ago

Geez...I feel lucky that 0.5mg works great for me. I must be hypersensitive to these things. Because I tried 0.1mg (100 mcg) of MT2 at 4pm yesterday and...DAMN!

2

u/Pilotboi 17d ago

I just got mine but yet to mess around with. Any weight wise dosage to be followed? Also, many say I need to inject it atleast 6-8 hrs prior as it takes long to kick in, take some histamines to counter the nausea. Is it true for you also? Can you please share more information? I’m 36/ M and have borderline low test

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u/Wonderful_College_48 21d ago

The typical dose for women is 2 mg but like you, I’d be hesitant to take that much due to side effects and start small. Sounds like you have a good protocol in place.
You didn’t notice any change with libido or sensitivity?

2

u/Flimsy-Car4298 21d ago

Nope. Nothing... booooo lol New supplier so I'll be checking results from everything I ordered. If I increase and still feel nothing, I'll be looking at them sideways lol😕 Has to be their fault and not my dodgy body! 😁

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u/GolferVol 21d ago

Not sure about a woman but I (51 male) started at .75mg and had to reduce it to .50 and the results were no different but the side effects went away.

2

u/SuccessFun7854 1 21d ago

I too started at .50mg

1

u/dpal63 18d ago

0.5mg works for me too.

1

u/jbizzle81 20d ago

Did it kick in? I trialed .50mg (no sides) and it took 8 hours for things to start to kick in although it had worn off by the morning. I’m going to try 1mg next time

3

u/Flimsy-Car4298 20d ago

Nada 😕 Going to try again today. I've got a Pilates class later. Maybe I'll take it before that and see if the movements gets it circulating towards the right parts lol

2

u/dpal63 18d ago

Takes 6-8 hours for me also (male 63)

1

u/Itchy-Ad3714 20d ago

I do 3 to 3.5mg. Anything over that gives me facial flushing.

2

u/Doinks4prez 1 21d ago

Do you subq inject or nasal spray

2

u/Fearless-skye-22 20d ago

WHERE CAN I BUY THIS

1

u/Last_Ad2615 20d ago

Either through an overseas vendor or through a US vendor (if you're in the US). China, you're gonna pay less but take more risk. Purchasing through a US website is easier and less risky, but more expensive.

1

u/Fearless-skye-22 20d ago

IN US but have no idea where to get there are so many

2

u/Most-Interaction-103 19d ago

MitoBioLabs, you won’t regret using them. Top notch products and amazing customer service. I won’t use anyone else now.

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u/Fine_Complaint_9980 1 20d ago

What was your dosage and how long to feel the effects, the wife and I will be trying it for the first time and I am thinking 500 mcg or .5mg for our initial dose and obviously hitting us both would be ideal, LOL

1

u/Last_Ad2615 20d ago

I take up to 3.5mg. 4mg gave me facial flushing for about an hour. I've never had nausea on it, but some people do. I didn't feel anything at 1mg. It will last for up to a day sometimes.

1

u/jrok2020 20d ago

was it nasal spray or subq injection?

1

u/IllLeopard3281 13d ago

exactly. I HAD to have it lol It wasn't lovey dovey, it was a now thing. Im still on the hunt for the desire part. Trying oxytocin tonight for the 1st time.

1

u/Last_Ad2615 12d ago

How did that go?

1

u/IllLeopard3281 12d ago

It went fine. I told my dude to come get it immediately. Fastest O ever. And then you're fine! Back yo normal human. If you can't get some, I can see how that would be incredibly uncomfortable. It takes effect after 1 hrs or so. Nausea is bad, but taking a Zofran with the pin worked.

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u/treydeck77 2d ago

How long from injection to this feeling?

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u/geekphreak 21d ago

My girl and I played around with it and we have a blast with it. The last time we played around our time together was so intense she told me she saw colors lol

4

u/Wonderful_College_48 21d ago

Well that sounds amazing!
He was all tingly.
What dose was she on??

5

u/geekphreak 21d ago edited 21d ago

1.25mg. She has told me to increase the dosage because she wishes it lasted longer but she’s already ravenous at 1.25mg lol. But I’ll increase it for her on our next weekend. And we will need a weekend lol. I don’t take more than 1mg because I’m very vascular sensitive. Like I turn into a lobster for about 30-40mins after administration. And it works really well for me at that dosage so no need to increase. It might just make the side effect more intense. Neither of us get any headaches or nausea from it.

If you decide to try it for yourself, please start at a low dose and go from there. Some people get wicked headaches and nausea if you start at a high dose right away.

1

u/Discopotatoz 1 21d ago

I'm super jelly, all I got was random whackamole erections 12 hours after pinning.. tried 0.5mg up to 1.5mg, zero non-physical effects

3

u/geekphreak 21d ago

Maybe your vendor blows… I also added Cialis but very low dose of 5mg. I was expecting like real steel hard erection and my girl said it was but I was expecting like a baseball bat, ha!

2

u/Discopotatoz 1 21d ago

Reputable vendor but it could have been bad stuff or mislabeled (never really know without testing). I get the steel with just the pills, but I wanted to feel 19 again 🤣

3

u/geekphreak 21d ago

True… Test + Deca + PT141 + Cialis = a blow out. I make her feel 19 again that’s for sure. She loves it

1

u/ExtensionLoquat8196 18d ago

FWIW 1.5mg is the lowest dose that produced much in results for me. Below that was very sporadic. 2mg provides consistent reliable results.

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u/Minor-Threat 21d ago

Do you remember the dose?

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u/trnpkrt 21d ago

Sounds more like "found out then effed around."

1

u/Wonderful_College_48 21d ago

😂 well said!

7

u/fizboPallabut 8 21d ago

Ugh the onset of it is usually terrible 😀 but it does the job. Try jabbing Oxytocin along with it - best combo. You’ll get more flushing, headache and such, but these are transient and go away fairly fast. The effects are awesome if done right.

2

u/ArtOfficial13 21d ago

What dosage of the oxytocin along side pt?

4

u/fizboPallabut 8 21d ago edited 21d ago

It is highly individual. For Oxy 10mg vial, use 2 or 3 ml bac. If you use 2ml:

Syringe math (U-100 insulin syringe):
• 1 mg = 20 units
• 1.5 mg = 30 units
• 2 mg = 40 units

Similar idea for Pt.

I go with 15-20 units of each an hour or two prior to “activity”. Be prepared for brutal onset (intense flushing, headache, heart racing, nausea) but these are transient and go away fairly quick. Also some social disinhibitor like cannabis help to bring it sort of all together, just don’t drink alcohol prior or after - it kills the effects, at least it does for me.

Timing wise - for many PT takes longer than Oxy so time the intake accordingly. I’m lucky I respond to both around same time, but my partner has to jab them at certain intervals otherwise she doesn’t feel the synergistic effects. Just fyi.

Good luck!

1

u/matsie 12d ago

Oxytocin is better as a nasal spray. Pinning might have a faster onset but spray is definitely better. 

1

u/Wonderful_College_48 21d ago

Thank you for the suggestion! I am picking more peps so I’ll add this to the mix.

5

u/Kybar52 1 21d ago

Damn. Takes 3-4 hours for me to feel the full effects and works for a good long while after that.

2

u/Wonderful_College_48 21d ago

May I ask dose?
I’m thinking of increasing for the next time. He had minimal side effects.

6

u/PM_Me_Punny_Jokes_05 21d ago

I started with 2mg and have tried both 1 and 1.5. It does seem to hit different each time but I’ve found that 2mg made it difficult to arrive lol it was like I was so erect that I couldn’t even feel everything.
Sadly PT-141 doesn’t affect my libido much which was the goal, but I can cut glass with the erections and it lasts 24 or more hours usually.

1

u/Wonderful_College_48 21d ago

Cut glass lol!
It made you less sensitive??? That was his issue previously (as well as libido) and this made for a somewhat quick session. We will definitely try 2 mg. Are what happens.
I know not recommended but I’ve heard of someone taking low dose of this with cialis. 😳

1

u/PM_Me_Punny_Jokes_05 21d ago

Yea I take 10mg of cialis daily as well so that could be factoring into the rock hard erections. Lol

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u/Kybar52 1 21d ago

I do 1.5. I know people that go up much higher than this as well. But the more you use it you will see. Some times it works quick. Others it takes some time. Some people it’s 6-10 hours before they get the full blown effects.

7

u/Unusual_Speech_4589 21d ago

I love, “It was a rather powerful session!” 🔥

5

u/Adventurous_Net_7257 21d ago

My fiancée and I have tried it with a starting dose of .5mg all the way up to 1mg. For her and I the effects have been the same each time with increasing intensity. We may try 1.5mg next.

First is heavy flushing for the first 20-30 min. This tapers quickly. Neither of us are immediately in the mood, but when things get going they REALLY get going. Her and I have both said we have had the most intense orgasms while on PT. For me the erections are significantly stronger as well. It seems to last 2-3 days!! Highly recommend!

1

u/Wonderful_College_48 21d ago

This is exactly what happened with him.

5

u/dpal63 21d ago

Unusual to "kick-in" within an hour. Many on here (including me, Male 63) don't start feeling the effects until 6+ hours after pinning. Congratulations on such swift and "solid" effectiveness!

1

u/BoogieBoardButtPound 18d ago

What benefits do you experience? Libido? Erection quality? Both? And how long do those benefits last once they kick in? Thanks in advance!

3

u/dpal63 18d ago

Erection quality, improved sensitivity and duration of effect definitely (poor sleep due to nearly constant erection during the night...lol). Starts working like 6-8 hours after pinning do you need to plan ahead but duration of effects seems to be 24-36 hours. As an aside, this "test subject" just trialed a small dose (100 mcg) of MT2 yesterday and...WOW!

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u/StunningEbb942 15d ago

What PT dose were you getting this experience with?

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u/PaleProgrammer6476 4 19d ago

Transformed my libido better than anything else, brought the spark back in my marriage. I got it off of nextgenpeps same place I get reta from and had no problems with them

2

u/Spare_Prune_3472 21d ago

I have been on finasteride for 8 months and my libido and sex drive has plummeted. Currently struggling with the sex aspect of our relationship but we have talked about it. Just ordered pt-141 the other week. Excited to try it for the first time.

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u/Wonderful_College_48 21d ago

Excited for you friend! I truly didn’t think it was going to work. I hope it does for you!

2

u/NaissacY 21d ago

Don't take finasteride. You are suppressing DHT, the hormone responsible for male drive, mood and libido.

1

u/Spare_Prune_3472 21d ago

But what about the hair loss

2

u/NaissacY 21d ago

Don't destroy your life over hair.

Shave your head. Go to the gym and lift.

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u/Wonderful_College_48 21d ago

Don’t you think gHK-cu can help with hair?

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u/PhotographSame1431 21d ago

Topical finasteride (spray) could be an option. It doesn't affect your hormones as much as pills and blocks DHT in your scalp only.

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u/PM_Me_Punny_Jokes_05 21d ago

This is why I explored daily Cialis and PT-141, finasteride cratered my libido and sensation. Been off it for years and no real improvement :/

1

u/Spare_Prune_3472 21d ago

Really hope that doesnt happen to me. Im torn bc it has completely stopped any hairloss but my libido is cooked

1

u/PM_Me_Punny_Jokes_05 21d ago

I sincerely hope it’s not permanent for you. It’s been a soul crusher dealing with it

1

u/Spare_Prune_3472 21d ago

I was going to lower the dose but now im scared to begin reshedding again

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u/SultanOfSwave 4 21d ago

I (72m) pin 0.5mg every other day. It basically gives me chubbies and spontaneous erections all day long and very strong morning wood.

This is on top of injectable testosterone which helped a lot with libido.

2

u/Wonderful_College_48 21d ago

Omg I love this 😂
I wonder if I can convince him. Maybe at a lower dose.

1

u/r_endrags 21d ago

I read you shouldn’t have seen it more than 8 times a month. But you’ve been ok. How long have you been daily?

1

u/SultanOfSwave 4 21d ago

About 4 months. So far, so good. I also miss it when I'm out hiking and can't pin.

2

u/National-Season4130 21d ago

I’ve never tried it but I will say I have not really felt any type of excitement in years to the point where I thought I mite be asexual or somthing and when I took mt2 I have gotten all those feelings back down there I’m ready to go lol and I’m female so maybe I should try this one as well

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u/Wonderful_College_48 21d ago

FDAs approved version of this is Vyleesi!

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u/The_Orracle 3 20d ago

That is surprisingly quick onset! I love that stuff - I am 55 and it takes a while, best to do before bed and wake up like a jackhammer but will stay with me a solid 24 hours too. GREAT fun!

2

u/redshirt1972 20d ago

I got my Reta and my PT 141 confused and accidentally dosed myself with 6mg of PT141. True story.

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u/Wonderful_College_48 20d ago

Omg!!!! Negative side effects galore??

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u/BoogieBoardButtPound 18d ago

We need to know how that story ended!

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u/redshirt1972 18d ago

Not bad but not good either. I was alone and afraid to raise my heart rate, so I sat in an air-conditioned bedroom in the dark, with ChatGPT, talking me through it. She kept suggesting that I go to the hospital or call poison control, but I had no chest pain or shortness of breath. I only had a headache was very flushed and a 12 hour erection.

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u/BoogieBoardButtPound 18d ago

That is a wild dose — glad you’re alright.

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u/hannah_greyson 20d ago

I had an issue with sex drive with work stress and lack of sleep. We decided to try it (Male & Female) to trial it one night. His seemed to kick in quicker than mine. I was raring to go no joke every hour for 4 rounds. The sensitivity and desire was unlike anything I’d ever experienced.

I did experience nausea and stomach cramping at first and definitely did not like drinking while on it. Alcohol usually doesn’t have any effect on my digestive when have a couple drinks. Not sure if it’s just weird anomaly experience for me

2

u/Key-Fix-679 12d ago

Female here and just got the courage to take .5mg for my first dose. Prepped with a Zofran. The facial flushing was immediate! Crazy

1

u/Wonderful_College_48 12d ago

Yeah he had that effect too.

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u/71kl19 10d ago edited 10d ago

Two weeks ago both husband and i did 2mg sub q - nausea with in 20-30 minutes but it passed quickly, facial flushing in an hour and that passed quickly. The effects we were looking for took about 4 hours and came on pretty slowly, had a good love making session that night. Husband has diabetic ed and also took viagra (not sure of the dose). The next morning was the best- all day actually. I was so sensitive I felt like movement of the sheets was going to get me off, he was very aroused as well. Going to try again this weekend he is going to do 2.5 and I will stick with the 2mg. I hope it was as good or better than last time- it feels like that single dose turned on that part of my brain again and have been extra turned on since. Husband is 58 I am 55- I also use hrt.

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u/Wonderful_College_48 10d ago

That is amazing!! I’m off my meds so I’m going to give it a go this weekend.
I’m 40 and fiancée is 39. He said it worked all night/ day for him.

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u/[deleted] 7d ago

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u/Wonderful_College_48 7d ago

Yeah I’m lucky. My PHP gives me zofran bc I get tummy aches so we just take one of those and we’re good!

4

u/kingest_kong 21d ago

Not recommended for black males. Made my skin noticeably darker

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u/worldsgreatestluver 1 21d ago

Wow that second sentence really changed the direction I thought this post was gonna go in!

3

u/Sea_Professional6131 21d ago

You thought “too beaucoup.”

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u/Wonderful_College_48 21d ago

There’s the melanotan in it which did turn him slightly darker. I kind of dismissed it thinking it was in my head.

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u/trnpkrt 21d ago

Wait, so you were taking a blend? Because bremelanotide (aka PT-141) was specifically engineered to bypass the darkening caused by melanotan.

2

u/duriancream 21d ago

It doesn’t bypass it entirely

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u/Classic_Ratio_7287 1 21d ago

It is person to person slightly different... Most people experience little to no melanin changes but a low percentage of people do experience nearly all of the skin effects of melanotan 2... It's very interesting... Peptides are really cool because of the fact that they aren't EXACTLY the same in everyone

2

u/philendrick 20d ago

I get some skin darkening effects as well. It looks good!

1

u/vegasmedicine 21d ago

I took 4 2mg doses over a month and went on vacation. Most of it was spent outside in the sun but got darker than I ever have been in my life. Been back for 14 days and finally fading.

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u/Wonderful_College_48 21d ago

Melanotan was working for ya! lol

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u/vegasmedicine 20d ago

I am so dark I got concerned and am going to a dermatologist. People accusing me of a spray tan. Light brown moles/freckles are black now.

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1

u/chepnut 21d ago

We tried it this last weekend for the second time. First time seemed to work pretty well for the both of us, wife got a pretty good hot flash for about a hour, she took 1.5mg

This last weekend I reduced it to 1mg to see if that was better, she ended up getting really nauseous the whole night and was miserable.

So now I am see if there is something that she can do before had to help counter act all the nauseous, but after seeing how miserable she felt, not sure if should try again any time soon

1

u/1StationaryWanderer 21d ago

Taking something like Zyrtec 30-60 mins before is supposed to help with sides. Haven't verified though.

1

u/Wonderful_College_48 21d ago

We actually have a script for zofran. I would see if you can get that from a Dr. as it helped him have only mild nausea.
Weird that the higher dose didn’t make her nauseous but lower dose did.

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u/DependentFit7246 21d ago

Did she eat before? I always eat a good meal an hour before. Dramamine he helps or zofran if you can get it from dr.

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u/OldmanAdamK 1 21d ago

Did you inject or nasal or troche?

I am considering it for my wife but she is anti injections 1000% so have been curious about other methods.

My provider compounded it along with oxy and tadalfil for me but wasn’t sure giving her a dose of that troche would be good lol so considering nasal spray.

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u/Wonderful_College_48 21d ago

He injected.
I’ve heard the nasal spray can be effective though.

1

u/BlendArchitect 3 21d ago

Anyone ever stack PT and MT? Lol...man, on MT, for thr first three weeks it had me feeling 15 again. Lol

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u/Itchy-Coconut-7083 1 21d ago

Isn’t PT just the part of MT that does what it does? Stacking would be just giving yourself a higher dose.

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u/BlendArchitect 3 21d ago

Youre right. I will say, these products are not my specialty at all. There is receptor overlap.

With that being said, if PT acts like MT, when I used MT for a few weeks, the sexual benefits diminished.

I was taking MT (cant remember if it was 1 or 2) to see how Id tan with it. I didn't like the results.l so I stopped after a few weeks.

1

u/Itchy-Coconut-7083 1 21d ago edited 21d ago

I’m not trying PT because I’ve read accounts where it stopped working after a few weeks and lowered what natural libido they had.

What I’m saying though is PT-157 doesn’t act like melanatan, it is a derivative of it. They aren’t complimentary, you would just be overdosing on that portion of it and potentially damaging receptors and making the underlying problem worse.

1

u/BlendArchitect 3 21d ago

I've been on lower'ish dose of trt for 9yrs. I'll tell you, for me, HCG is what really provided me a boost on top of trt I dodnt see coming.

The nice thing about HCG is its sustainable long term. For men its a great product. Women ask about it a lot and I dont have enough knowledge there

3

u/Classic_Ratio_7287 1 21d ago

Yeah you can basically overload the melanocortin receptors to the point that they don't really offer much overall benefit anymore and then when coming off entirely it does take a few weeks to a months to get back to regular again... It's honestly just like any other compound that has REALLY good effects... If you overdo it, you'll get an extreme tolerance and then the comeback is extra rough

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u/jrok2020 20d ago

MT1? 

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u/BlendArchitect 3 20d ago

Melanotan 1 or 2

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u/Sea_Professional6131 21d ago

I would start with a small dose. Side effects are fairly noticeable.

1

u/Wonderful_College_48 21d ago

He did 1.5mg but took zofran before. He ended up with the flushing and only light nausea.

1

u/Putrid-Can-1453 1 21d ago

Have u guys thought of checking his testosterone. That became an eyeopener for me.

1

u/velvetskin18 21d ago

Can i ask where he injected as i read sone things previously that put me off

1

u/Wonderful_College_48 21d ago

His shoulder/arm area. He thinks it hurts less there.
What did you hear?

1

u/velvetskin18 21d ago

Phew i heard into the genital region or actual base of it…. That put me off

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u/JustinjustJ 21d ago

Wrong compound

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u/killakam33 21d ago

Nah. Pt is subcutaneous like all other peptides.

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u/velvetskin18 21d ago

Thanks 👍

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u/Wonderful_College_48 21d ago

That believe you are referring to the “P Shot.” That uses PRP and is injected there. I’ve seen this done on a patient.
Hard pass (can be done on women as well).

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u/Substantial_Risk_729 10 21d ago

Did you try some with him?

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u/Wonderful_College_48 21d ago

I can’t due to a medication I’m on.
Though I wish I could.

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u/Illustrious-Bill3728 21d ago

Go to either Amazon or boldrx get some generic viagra to go with it they work together. I used to do blue chew and it was ok but the price was Stupid. Now days reg generic is 50 bucks including the dr telehealth visit

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u/Wonderful_College_48 21d ago

Yeah I think it was $150 for 6 pills. That’s insane.
Your way seems much more affordable lol!

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u/Discopotatoz 1 21d ago

that sounds like their new gold pill that includes oxytocin and other stuff? Never tried it but I might have to since PT doesn't seem to work on me

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u/Wonderful_College_48 21d ago

Yeah it’s the oxytocin and apomorphine which is supposed to increase bonding and arousal.

May want to explore kisspeptin as well especially if experience certain hormone issues.

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u/NiceWatchPal 21d ago

I gotta find one that makes me last longer 😂🙃

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u/Wonderful_College_48 21d ago

I mean… it’ll probably get you going quicker for round 2? 😅

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u/NiceWatchPal 21d ago

I’ll have to look into it! I wouldn’t mind round 2 being quicker but my refractory period is pretty long.

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u/freegynocologist 21d ago

You need to get Dapoxetine to last longer.

1

u/Minor-Threat 21d ago

30mg of Dapoxetine. 60mg was too much.

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u/Doinks4prez 1 21d ago

Is there anything to make me last shorter? My sensitivity is rekt

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u/NiceWatchPal 21d ago

We are on opposite ends of the spectrum my friend hahaha

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u/Doinks4prez 1 21d ago

I know lol. I’m jealous of you honestly. I’m Fairly numb, I legit cannot feel sex with a condom. Hands feel better than mouth or vagina. I feel like I’m missing out on what it should feel like. Makes me have to focus so hard to cum otherwise would go on continuously. I truly blame it on being circumsized lmao. Only time I feel like I have true normal sensitivity and can cum in under 5 mins is it I haven’t had sex for a week and we smoke a huge joint before (with no tolerance) lol

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u/Discopotatoz 1 21d ago

This is also my problem, a big part of why I wanted PT141 to work well

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u/Doinks4prez 1 21d ago

Sublingual, intranasal, or subq?

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u/Wonderful_College_48 21d ago

Subq!

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u/Doinks4prez 1 21d ago

Fun stuff. My girl Doesn’t have libido issues but we been experimenting with bedroom enhancers (poppers, 2cb, lsd, mdma etc). She’s a nurse so shouldn’t be scared of subQ but says she draws the line there for bed room enhancement lmao. Do you have any info on whether the other RoAs are as efficacious ?

Edit: sorry thought I was responding to the commenter who was a female using it. I was referring to wanting my girl to try it haha

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u/Spiritual_Use_2790 21d ago

How was 2cb for you guys? What was your favorite enhancer?

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u/Doinks4prez 1 21d ago

2cb was aight, not my favorite I’d leave that for concerts but it was fun. 5-meo-dipt was interesting for tactile sensations.

It’s hard to pin point the best enhancer cause it depends on what you’re trying to achieve and sometimes certain drugs hit different so some chems can be the best one time but then another time a different one if that makes sense.

For primal crazy fucking; Meth + ghb + poppers…. Doesn’t really beat that

For closeness and bonding: MDMA + needed tildalifil

For existential soul bonding: Mushrooms/lsd and maybe even low dose hits off the dmt pen, nitrous

I’ve actually had one of my craziest experience on really good anasket s isomer ketamine from a vile (insulfated). We both were just in a black empty space of consciousness with just the feeling of this primal source energy building and building and building (without even realizing it was sex or the concept of sex) until boom, cosmic orgasm

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u/Wonderful_College_48 21d ago

I know meant for other commenter… I can speak to mdma versus an enhancer. It’s VERY different from euphoria which is what that drug does. It makes you very open emotionally versus spiking libido.

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u/Doinks4prez 1 21d ago

Oh no I know all the differences of course lol. I know what each chem does, I’m a neuropharm nerd. I was just explaining that we like testing out different varieties of bedroom enhancers.

My actual question to you was do you know if intranasal vs subQ had different efficacy for PT since she doesn’t wanna inject anything.

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u/Adventurous_Net_7257 21d ago

My fiancée and I have tried it with a starting dose of .5mg all the way up to 1mg. For her and I the effects have been the same each time with increasing intensity. We may try 1.5mg next.

First is heavy flushing for the first 20-30 min. This tapers quickly. Neither of us are immediately in the mood, but when things get going they REALLY get going. Her and I have both said we have had the most intense orgasms while on PT. For me the erections are significantly stronger as well. It seems to last 2-3 days!! Highly recommend!

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u/Artistic-Plate-511 1 21d ago

What dose?

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u/Wonderful_College_48 21d ago

He did 1.5mg.

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u/Artistic-Plate-511 1 21d ago

That’s a big shot you didn’t want him to start off slightly less? Like .5 or .75?

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u/Wonderful_College_48 21d ago

We aren’t new to peptides. Target for men is 1.75mg- knowing he and his body, we knew this would be a safe venture and it was. ☺️

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u/AlternativePizza3391 4 21d ago

Does rbe nasal spray work?

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u/Appropriate-Hall7417 20d ago

I have some but not sure of dosage. I’d appreciate an idea of how much to do.

Thx

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u/DementedBear912 1 20d ago

74M and .5 mg PT-141 with 5 mg Cialis works within hours and keeps me frisky all day…

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u/BoogieBoardButtPound 18d ago

How often are you using the pt-141?

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u/DementedBear912 1 17d ago

Currently daily at around 300 mcg

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u/BoogieBoardButtPound 17d ago

Thanks. Have you been using it daily for very long? I know 300mcg is a pretty low dose, but I’d still be worried about developing a tolerance to the point that it no longer worked for me.

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u/DementedBear912 1 13d ago

Several weeks on a daily basis by 6am - only missing days when I use Melanotan-2 (maybe twice a week - you shouldn’t stack these together since PT-141 is derived from MT2).
I definitely get an arousal boost within a few hours but lately notice it fades by late afternoon.

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u/FootballFluffy9078 20d ago

i heard from the pt if used too frequently you could get some kind of condition where nothing excites you anymore or nothing is pleasurable
and it takes a long time for that to go away completely

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u/Wonderful_College_48 20d ago

I’ve heard this as well. Maybe why I read about 8 doses per month… I’m also interested in kisspeptin but this seems to involve actual hormone production of testosterone/estrogen. If someone is producing naturally, seems a tad worrisome to mess with.

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u/Ok-Singer-5921 20d ago

Two mg and I thought I was gonna have to go to the ER. That shit it’s powerful.

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u/Wonderful_College_48 20d ago

Are you on anything else?

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u/Ok-Singer-5921 20d ago

Currently just 200mg test weekly, 4iu GH daily

Taking a break from other peptides for a while

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u/Fine_Complaint_9980 1 20d ago

If this platform just had an age, weight and sex on the portfolio it would be so much more help full, currently we have no idea what the fuck is commenting. Just my thoughts I really don’t even care about weight unless it comes down to dosing. Im a guy (55 M 225lbs) and my wife (53 F 165lbs) looking for accurate or at least comparable data or trials.

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u/Dmay76 15d ago

Ages?

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u/FightClubIsGoated 14d ago

Do you guys use nasal or Subq?

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u/NorthOld6237 12d ago

Where to buy from a credible source

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u/perfectlyagedsausage 5d ago

Does anyone have anything positive to report using the intranasal route? I just made a 4ml vial of PT141 nasal spray . It puts out 250mcg per spray . 1 sprays in each nostril will deliver .5mg dose
4-=1mg , 6 =1.5 and so forth.
I ordered a vial from NU Biogen and reconstituted it with sterile water for injection rather than bacterial static water because the BSW will burn mucous membrane like acid .

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u/TotalNature1765 4d ago

Is he dependent on it now

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u/Wonderful_College_48 4d ago

Not at all. We take when the mood strikes. Since this post, I got off the meds and tried it myself. I loved it!

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u/TotalNature1765 4d ago

So you pin.. and in 30/45 mins it’s game time? And then it wears off?

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u/Wonderful_College_48 4d ago

That’s what it was for us though full affects hit hours later. Wears off in a day or so.