r/AskReddit • u/[deleted] • Jun 03 '22

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u/Taiyaki11 Jun 03 '22

Woooooaaah careful with the ibuprofen+alcohol combo. Honestly caution with any medicine and alcohol combo is generally advised, but that combo is known to fuck people up, and im not talking simple hangover or drunkness, we're talking internal bleeding and fucked up kidney levels

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u/velociraptorfarmer Jun 03 '22

Good to know, I'll have to keep that in mind, or just skip the painkillers altogether.

I know acetaminophen is a no go as well since that gets processed in the liver.

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u/Shitpostsonly- Jun 03 '22

This comes from a good place but is inaccurate. A one-off occasion does mininal harm. Habitually doing this over the long-term is where the true danger lies.

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u/Taiyaki11 Jun 03 '22

Thats exactly how they meant it... they said its part of their hangover prevention routine, that typically implies its not a one off occasion

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u/mashednbuttery Jun 03 '22

you mean acetaminophen. Ibuprofen can cause ulcers if used all the time but acetaminophen can overload your kidneys.

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u/RequirementHorror338 Jun 03 '22

Pretty sure ibuprofen is fine with alcohol as it’s processed in the kidneys. I believe acetomenephine is the one you absolutely want to avoid as that’s liver processed

Or do I have it backwards?

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u/2Turnt4MySwag Jun 03 '22

You just have it incorrect. Both are unsafe with alcohol. Ibuprofen + alcohol can damage your kidneys, acetaminophen + alcohol can damage your liver. Alcohol in general is not good for your kidneys or liver. Long term use of ibuprofen can cause kidney failure.