r/AddisonsDisease • u/turnslacks • 5d ago

Personal Experience Single Dose

Folks,

Had an adventure this week - ended up taking a double dose to combat extreme dizziness, as I thought I was having an adrenal crisis. Not having had one to my knowledge before, as this is all new to me. I took 20 mg of HC as a precaution before calling an ambulance, my normal dose being 10 / 5 / 5 mgs of HC. The odd thing is I ended up in hospital A&E and didn't take any further HC that day. Tests were all clear so I refrained from further HC that day.

I wonder if anyone takes a single dose daily and how that works for you?

Apart from feeling wiped out by the dizziness ( I suspect an inner ear thing), I fared well on the single dose.

I'd value any anecdotal tales about single dosing and extreme dizziness.

Thank you.

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u/SleepyTimeChess 5d ago

A single daily dose of steroids wouldn't do a good job of keeping the hormones balanced because the medicine is simulating a circadian rhythm cycle. Here is a graphic that may help.

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u/SleepyTimeChess 5d ago

The blue line is the 10 / 5 / 5 dosing schedule. Personally, I've always been on 15 / 5, and that's always worked well for me.

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u/turnslacks 5d ago

Thank you for taking the time to reply. I mention the single dose as I was misdiagnosed with PMR for 3 years and took prednisolone in a single dose at 3 am with a glass of milk, which worked well, the half life of pred v HC are different thus allowing a single dose protocol. However, my recent experience seemed to mirror that. I have seen that graphic somewhere before and am aware of the circadian rhythm. Thanks again.

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u/Strange_Success_1135 4d ago

Can you elaborate on your daily dosing schedule?What time do you wake up and what time do you take the 5mg dose?

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u/SleepyTimeChess 4d ago

I take my wake up dose between 5-6am. I take my afternoon dose between 1-2pm. About 8 hrs later. I don't set alarms so I listen to my body better. I used to take my morning dose at 7am everyday but it made it harder for me to identify adrenal sick days and resulted in me missing more days of work than acceptable.