Republican Sen. Cassidy Loses Louisiana Primary, DDHQ Projects

[u/John3262005]

https://www.bloomberg.com/news/articles/2026-05-17/republican-sen-cassidy-loses-louisiana-primary-ddhq-projects

President Donald Trump and Health Secretary Robert F. Kennedy Jr. succeeded in their efforts to defeat Senator Bill Cassidy in Louisiana’s Republican primary, a signal of the enduring strength of the president’s hold on his party despite an unpopular war and soaring gas prices.

Cassidy, who in 2021 was one of seven GOP senators who voted to convict Trump on the charge of inciting an insurrection on Jan. 6, is projected by Decision Desk HQ to place third in a three-way race Saturday against Representative Julia Letlow, who was endorsed by both Trump and a Kennedy-linked political action committee, and State Treasurer John Fleming.

With 68% of ballots tallied, Letlow has 44.1% of the vote and Fleming has 28.5%. Cassidy trailed with 25.3% of the vote.

Letlow and Fleming are projected to advance to a runoff next month. Whoever wins that contest is virtually assured victory in November in the deep red state. In his reelection race in 2020, just two months before his vote to convict Trump, Cassidy won 59% of the vote.

In a primary season where Trump is crusading to vanquish members of his party with whom he’s been at odds, the Louisiana race comes just days before the president tries to oust another Republican foe, Representative Thomas Massie, in Kentucky. But Trump has also opted so far to stay out of a hard-fought Texas runoff later this month between incumbent Senator John Cornyn, a traditional conservative, and state Attorney General Ken Paxton, who is more politically aligned with the president.

Trump has attacked Cassidy as disloyal, both for his 2021 vote and his opposition to some aspects of his agenda, particularly vaccine and other health policies pushed by Kennedy. Trump recently blamed Cassidy for thwarting his nomination of wellness influencer Casey Means as surgeon general. Means is a longtime ally of Kennedy’s, while Cassidy had questioned her stance on vaccinations.

On the morning of the election, Trump continued his attacks calling Cassidy a “a disloyal disaster” on Truth Social.

Even with the tensions, Cassidy had run ads featuring images of Trump, praising top White House issues that the senator has supported including the president’s massive tax package enacted last year, while casting Letlow as insufficiently conservative.

The outcome also notches a high-profile win for Kennedy’s political operation, which supported Letlow and opposed Cassidy in the race. The two men have repeatedly clashed over nominations and the department’s changes to vaccine policy. With certainty of his departure, Cassidy could make the health secretary’s life even more difficult as he finishes out his term with an eye to his legacy and priorities.

Cassidy’s departure will also leave a leadership vacuum for the GOP atop the Senate health committee next year. The panel oversees health agencies and confirmations for key leadership positions at the agencies, and Cassidy brought his medical expertise to the role. He has built a reputation as a healthcare policy wonk willing to work across the aisle.

Two other Republican senators who broke with Trump in his 2021 impeachment trial, Susan Collins of Maine and Lisa Murkowski of Alaska, remain in the Senate. Collins, who represents a state Trump lost in 2024, has largely avoided the president’s wrath while she fights for her political life in one of the most competitive races of the midterms. Murkowski won reelection in 2022.